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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Antibody‐dependent cell‐mediated cytotoxicity against epstein‐barr virus membrane antigen in african Burkitt's lymphoma
International Journal of Cancer, Volume 24, No. 5, Year 1979
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Description
Serial samples of sera from patients with African Burkitt's lymphoma were tested for antibody against Epstein‐Barr virus (EBV)‐specific membrane antigen (MA) by the antibody‐dependent cell‐mediated cytotoxicity assay (ADCC). Titers of patients in the long‐term survivor group were generally higher than those found in the sera of patients in the short‐term survivor group. Although ADCC titers to EBV‐MA were not useful in predicting which patients would relapse there was a definite relationship between ADCC titer and prognosis. The individual differences in ADCC titers in patients in remission may explain the variability of responses that have been reported in studies on serotherapy with remission plasma. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company
Authors & Co-Authors
Granlund, David J.
United States, Kensington
Litton Bionetics, Inc.
Nkrumah, Francis K.
Ghana, Accra
University of Ghana
Perkins, Ida Virginia
United States, Bethesda
National Institutes of Health Nih
Biggar, Robert John
United States, Bethesda
National Institutes of Health Nih
Levine, Paul H.
United States, Bethesda
National Institutes of Health Nih
Fuccillo, David A.
United States, Kensington
Litton Bionetics, Inc.
Statistics
Citations: 7
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1002/ijc.2910240508
ISSN:
00207136
e-ISSN:
10970215