Hemostatic potential of the sap of Musa sapientum L. (Musaceae)

In Benin, Musa sapientum is one of the most important medicinal species used in the treatment of bleeding. In this study, hemostatic properties of M. sapientium sapand its mechanism of action have been identified through hematologic tests such as Clotting Time, Prothrombin Time, Activated Partial Thromboplastin Time and Milk Precipitation Test; biochemical test (total proteins); macroscopic and microscopic tests performed on different blood products before and after addition of sap. The results obtained showed that Musa sapientum reduced significantly clotting Time. However, it has no effect on the individual factors of coagulation. Its mechanism of action results from its ability to form a protein network which is a basis for cellular aggregation stopping bleeding. Moreover, Milk Precipitation Test showed astringent properties of Musa sapientum and therefore its vasoconstrictors properties. Phytochemical analyses revealed the presence of alkaloids, tannins, coumarins, reducing compounds, anthocyanins and leucoantocyanes. M. sapientumis great on treatment of bleeding and could help to elaborate new drugs.