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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Rosai-Dorfman disease presenting as bilateral eyelid swellings
Medical Principles and Practice, Volume 15, No. 2, Year 2006
Notification
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Description
Objective: To report a case of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) in an extranodal site with unusual presentation. Case Presentation: A 19-year-old girl presented with bilateral upper eyelid swellings of 2 years duration due to tumor. The masses were excised and sent for histopathological examination. Microscopic examination revealed similar features in both masses in the form of a collection of large histiocytic cells showing emperipolesis (lymphocytophagocytosis). The histiocytic cells stained positive-ly with S-100 protein and CD68. The background comprised small lymphocytes and plasma cells. Based on the overall features a diagnosis of sinus histiocytosis with massive lymphadenopathy or Rosai-Dorfman disease was made. Conclusion: The present case highlights one of the forms in which extranodal Rosai-Dorfman disease can manifest itself. It is important to keep this differential diagnosis in mind whenever such histopathological features are encountered. Copyright © 2006 S. Karger AG.
Authors & Co-Authors
Jogai, Sanjay
Kuwait, Shuwaikh
Hussain Maki al Juma Centre for Specialized Surgeries
United Kingdom, Salisbury
Salisbury District Hospital
Temmim, Labiba L.
Kuwait, Shuwaikh
Hussain Maki al Juma Centre for Specialized Surgeries
Al-Baghli, Abdullah
Kuwait
Abdul Rahman Al-bahar Eye Center
Adesina, A. O.
Kuwait, Shuwaikh
Hussain Maki al Juma Centre for Specialized Surgeries
Statistics
Citations: 7
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1159/000090925
ISSN:
10117571
Research Areas
Cancer
Participants Gender
Female