Publication Details

AFRICAN RESEARCH NEXUS

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chemistry

Synthesis, Structure, and Antiproliferative Activity of Ruthenium(II) Arene Complexes of Indenoisoquinoline Derivatives

Organometallics, Volume 35, No. 17, Year 2016

Novel ruthenium complexes of indenoisoquinoline derivatives were synthesized and characterized. The structure of the complex 9 was determined by single-crystal X-ray crystallography. Ruthenium complexes displayed strong DNA interactions. The cytotoxic activity of the complexes was tested against five cancer cell lines (MDA-MB-231, MCF-7, HEK-293, HT-29, and DU-145).

Statistics
Citations: 14
Authors: 14
Affiliations: 3
Identifiers
Doi: 10.1021/acs.organomet.6b00440
ISSN: 02767333
e-ISSN: 15206041
Research Areas
Cancer
Genetics And Genomics

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