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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Correlates of hepatitis C virus infection among incarcerated Ghanaians: A national multicentre study
Journal of Medical Microbiology, Volume 56, No. 3, Year 2007
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Description
A national multicentre cross-sectional study was undertaken on the correlates of hepatitis C virus (HCV) infection in a sample of inmates from eight Ghanaian prisons. A total of 1366 inmates from eight of the ten regional central prisons in Ghana were enrolled between May 2004 and December 2005. Subjects voluntarily completed a risk-factor questionnaire and provided blood specimens for unlinked anonymous testing for the presence of antibodies to HCV. These data were analysed using both univariate and multivariate techniques. The median age of participants was 36.5 years (range 16-84 years). Of the 1366 inmates tested, HCV seroprevalence was 18.7%. On multivariate analysis, the independent determinants of HCV infection were being incarcerated for longer than the median time served of 36 months [odds ratio (OR) 5.8; 95% confidence interval (95% CI) 5.0-6.9], history of intravenous drug use (OR 4.5; 95% CI 3.8-5.4) and homosexuality (OR 3.1; 95% CI 2.5-3.9). Consistent with similar studies worldwide, the prevalence of HCV in prison inmates was higher than the general population in Ghana, suggesting probable transmission in prisons in Ghana through intravenous drug use and unsafe sexual behaviour. © 2007 SGM.
Authors & Co-Authors
Adjei, Andrew Anthony
Ghana, Accra
University of Ghana
Armah, Henry B.
Ghana, Accra
University of Ghana
United States, Pittsburgh
University of Pittsburgh Medical Center
Gbagbo, Foster
Ghana, Accra
University of Ghana
Ampofo, William Kwabena
Ghana, Accra
University of Ghana
Quaye, Ike Kweku E.
Ghana, Accra
University of Ghana
Hesse, Ian F.A.
Ghana, Accra
University of Ghana
Mensah, George A.
Ghana, Accra
University of Ghana
Statistics
Citations: 31
Authors: 7
Affiliations: 2
Identifiers
Doi:
10.1099/jmm.0.46859-0
ISSN:
00222615
Research Areas
Infectious Diseases
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Case-Control Study
Study Approach
Quantitative
Study Locations
Ghana