Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Schistosoma haematobium infection and morbidity before and after large-scale administration of praziquantel in Burkina Faso
Journal of Infectious Diseases, Volume 196, No. 5, Year 2007
Notification
URL copied to clipboard!
Description
Background. In sub-Saharan Africa, 112 million people are infected with Schistosoma haematobium, with the most intense infections in children 5-15 years old. Methods. We describe a longitudinal epidemiological study that evaluates the relationship between S. haematobium infection and associated morbidity in children before and after the large-scale administration of praziquantel for schistosomiasis and albendazole for soil-transmitted helminths. Results. At baseline, higher intensities of S. haematobium infection were observed in children with anemia and/or severe microhematuria, but there was no apparent association between the risk of undernutrition and intensity of S. haematobium infection. Significant reductions in the prevalence and intensity of S. haematobium infection 1 year after treatment were, however, observed. Children who benefited the most from anthelmintic treatment in terms of increased hemoglobin concentrations were those who had anemia at baseline and those with highly positive microhematuria scores at baseline. Conclusions. This study suggests that even a single round of mass chemotherapy can have a substantial impact on S. haematobium infection and its associated morbidity in children. © 2007 by the Infectious Diseases Society of America. All rights reserved.
Authors & Co-Authors
Koukounari, Artemis
United Kingdom, London
Imperial College London
Gabrielli, Albis Francesco
Switzerland, Geneva
Organisation Mondiale de la Santé
Touré, Seydou
Burkina Faso, Ouagadougou
Ministere de la Sante Ouagadougou
Bosqué-Oliva, Elisa
United Kingdom, London
Imperial College London
Zhang, Yaobi
United Kingdom, London
Imperial College London
Sellin, Bertrand
Unknown Affiliation
Donnelly, Christl A.
United Kingdom, London
Imperial College London
Fenwick, Alan
United Kingdom, London
Imperial College London
Webster, Joanne P.
United Kingdom, London
Imperial College London
Statistics
Citations: 159
Authors: 9
Affiliations: 3
Identifiers
Doi:
10.1086/520515
ISSN:
00221899
Research Areas
Cancer
Food Security
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Burkina Faso