Antioxidant, compositional evaluation and blood pressure modulating potentials of bryophyllum pinnatum (Lam.), Viscum album (L.) and Artocarpus altilis (Parkinson) leave extracts

Bryophyllum pinnatum (Lam.), Viscum album (L.) and Artocarpus altilis (Parkinson) are medicinal plants widely used based on their ethnomedicinal properties in the regulation of blood pressure. This study was designed to evaluate the antioxidant activities and compositional constituents of these plants. The antioxidant potentials were analyzed using DPPH and FRAP assays, while Folin-Ciocalteu method was employed in the determination of the total phenolic antioxidant contents. Compositional analyses of the leave extracts were determined using Gas Chromatograghy-Mass Spectrophotometer (GC-MS). The total phenolic contents in Bryophyllum pinnatum, Artocarpus altilis and Viscum album were revealed as; 659.50 ±0.02, 1667.50 ±0.03, 1232.00 ±0.02 mg GAE.100 g-1 respectively. Considering the antioxidant activities, Artocarpus altilis leaf extract showed inhibitory activity on DPPH with IC50 of 2.24 ±0.26 mg.mL-1, Bryophyllum pinnatum and Viscum album with IC50 values 3.63 ±0.07 and 4.65 ±0.06 mg.mL-1 respectively. The FRAP in mg. GAE-1 for Artocarpus altilis, Bryophyllum pinnatum and Viscum album revealed; 2505.20 ±0.04, 1561.80 ±0.01 and 1698.00 ±0.03 respectively. GC-MS identified some vital phenolic components and essential fatty acids in the plants. The findings therefore suggest that; the plants if properly utilized, it could serve as alternatives in regulating blood pressure.