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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Antimicrobial susceptibility profile of neisseria gonorrhoeae isolated from patients attending a std facility in maputo, mozambique
Sexually Transmitted Diseases, Volume 36, No. 6, Year 2009
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Description
Objective: To ascertain the effectiveness of kanamycin for the treatment of gonorrhoea in Maputo, Mozambique. Methods & Design: A cross-sectional study design was employed. Urethral and cervical specimens were collected for the isolation of Neisseria gonorrhoeae from patients attending Centro de Saúde do Porto. Antimicrobial susceptibilities were determined for kanamycin, spectinomycin, ciprofloxacin, ceftriaxone, cefixime, tetracycline and penicillin. Results: Twenty-two (40%) Neisseria gonorrhoeae isolates were intermediate and 4(7%) were resistant to kanamycin; 42(77%) displayed high level resistance to tetracycline (MIC ≥ 16 mg/L); 34 (65%) were penicillinase producers, and 52 (95%) had spectinomycin MICs of 64 mg/L. All isolates were susceptible to ciprofloxacin (MIC ≤= 0.06 mg/L), ceftriaxone (MIC ≤ 0.015 mg/L) and cefixime (MIC ≤ 0.015 mg/L). Conclusion: The observations underscore the need for broader susceptibility surveillance studies to elucidate the pattern and extent of drug resistance in Mozambique. A review of the current treatment guidelines for genital discharge syndrome is warranted. © 2009 American Sexually Transmitted Diseases.
Authors & Co-Authors
Apalata, Teke Ruffin
South Africa, Durban
The Nelson R. Mandela Medical School
Zimba, Tomás Francisco
South Africa, Durban
The Nelson R. Mandela Medical School
Mozambique, Maputo
Hospital Central de Maputo
Sturm, Willem A.
South Africa, Durban
The Nelson R. Mandela Medical School
Moodley, Prashini
South Africa, Durban
The Nelson R. Mandela Medical School
Statistics
Citations: 32
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1097/OLQ.0b013e3181982e3c
ISSN:
01485717
Research Areas
Health System And Policy
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Mozambique