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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Reduced fertility and fecundity among patients with bipolar I disorder and schizophrenia in Egypt
Psychiatry Investigation, Volume 8, No. 3, Year 2011
Notification
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Description
Objective To evaluate reproduction among patients with bipolar I disorder (BP1) or schizophrenia (SZ) in Egypt. Methods BP1 patients (n=113) were compared with community based, demographically balanced controls (n=124) and SZ patients (n=79, DSM-IV). All participants were evaluated using structured interviews and corroborative data were obtained from relatives. Standard indices of procreation were included in multivariate analyses that incorporated key demographic variables. Results Control individuals were significantly more likely to have children than BP1 or SZ patients (controls 46.8%, BP1 15.9%, SZ 17.7%), but the BP1-SZ differences were non-significant. The average number of children for BP1 patients (0.37±0.9) and SZ patients (0.38±0.9) was significantly lower than for controls (1.04±1.48) (BP1 vs controls, p<0.001; SZ vs controls, p<0.001). The frequency of marriages among BP1 patients was nominally higher than the SZ group, but was significantly lower than controls (BP1: 31.9% SZ: 27.8% control: 57.3%). Even among married individuals, BP1 (but not SZ) patients were childless more often than controls (p=0.001). The marital fertility, i.e., the average number of children among patients with conjugal relationships for controls (1.8±1.57) was significantly higher than BP1 patients (1.14±1.31, p=0.02), but not significantly different from SZ patients (1.36±1.32, p=0.2). Conclusion Selected reproductive measures are significantly and substantially reduced among Egyptian BP1 patients. The reproductive indices are similar among BP1 and SZ patients, suggesting a role for general illness related variables. Regardless of the cause/s, the impair-ment constitutes important, under-investigated disability. © 2011 Korean Neuropsychiatric Association.
Authors & Co-Authors
Mansour, Hader A.
United States, Pittsburgh
Upmc Western Psychiatric Hospital
Egypt, Mansoura
Faculty of Medicine
Kandil, Kareem
United States, Pittsburgh
Upmc Western Psychiatric Hospital
Wood, Joel A.
United States, Pittsburgh
Upmc Western Psychiatric Hospital
Fathi, Warda
Egypt, Mansoura
Faculty of Medicine
Elassy, Mai
Egypt, Mansoura
Faculty of Medicine
Ibrahim, Ibtihal Mohamed Aly
Egypt, Mansoura
Faculty of Medicine
Salah, Hala
Egypt, Mansoura
Faculty of Medicine
Yassin, Amal
Egypt, Mansoura
Faculty of Medicine
Elsayed, Hanan
Egypt, Mansoura
Faculty of Medicine
Tobar, Salwa Salah
Egypt, Mansoura
Faculty of Medicine
El-Boraie, Hala Ahmed
Egypt, Mansoura
Faculty of Medicine
Eissa, Ahmed Ibrahim
Egypt, Mansoura
Faculty of Medicine
Elhadidy, Mohamed M.
Egypt, Mansoura
Faculty of Medicine
Ibrahim, Nahed E.
United States, Pittsburgh
Upmc Western Psychiatric Hospital
El-Bahaei, Wafaa
Egypt, Mansoura
Faculty of Medicine
Nimgaonkar, Vishwajit Laxmikant
United States, Pittsburgh
Upmc Western Psychiatric Hospital
United States, Pittsburgh
University of Pittsburgh Graduate School of Public Health
Statistics
Citations: 16
Authors: 16
Affiliations: 3
Identifiers
Doi:
10.4306/pi.2011.8.3.214
ISSN:
17383684
Research Areas
Disability
Maternal And Child Health
Mental Health
Sexual And Reproductive Health
Study Locations
Egypt