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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
PopAffiliator: Online calculator for individual affiliation to a major population group based on 17 autosomal short tandem repeat genotype profile
International Journal of Legal Medicine, Volume 125, No. 5, Year 2011
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Description
Because of their sensitivity and high level of discrimination, short tandem repeat (STR) maker systems are currently the method of choice in routine forensic casework and data banking, usually in multiplexes up to 15-17 loci. Constraints related to sample amount and quality, frequently encountered in forensic casework, will not allow to change this picture in the near future, notwithstanding the technological developments. In this study, we present a free online calculator named PopAffiliator ( http://cracs.fc.up.pt/popaffiliator ) for individual population affiliation in the three main population groups, Eurasian, East Asian and sub-Saharan African, based on genotype profiles for the common set of STRs used in forensics. This calculator performs affiliation based on a model constructed using machine learning techniques. The model was constructed using a data set of approximately fifteen thousand individuals collected for this work. The accuracy of individual population affiliation is approximately 86%, showing that the common set of STRs routinely used in forensics provide a considerable amount of information for population assignment, in addition to being excellent for individual identification. © 2010 Springer-Verlag.
Authors & Co-Authors
Pereira, Luísa
Portugal, Porto
Faculdade de Medicina da Universidade do Porto Fmup
Alshamali, Farida H.
United Arab Emirates, Dubai
General Department of Forensic Sciences and Criminology
Andreassen, Rune J.
Norway, Oslo
Oslomet – Storbyuniversitetet
Ballard, Ruth E.
United States, Sacramento
California State University, Sacramento
Chantràtita, Wasun
Thailand, Bangkok
Ramathibodi Hospital
Cho, Nam-soo
South Korea, Daejeon
National Institute of Scientific Investigation
Coudray, Clotilde
France, Toulouse
Université Toulouse Iii - Paul Sabatier
Dugoujon, Jean Michel H.
France, Toulouse
Université Toulouse Iii - Paul Sabatier
Espinoza, Marta
Costa Rica, San Jose
Poder Judicial
González-Andrade, Fabricio
Ecuador, Quito
Hospital Metropolitano
Hadi, Sibte
United Kingdom, Preston
University of Central Lancashire
Immel, Uta Dorothee
Germany, Halle
Martin-luther-universität Halle-wittenberg
Marian, Catalin Valer
United States, Washington, D.c.
Georgetown Lombardi Comprehensive Cancer Center
González-Martı́n, Antonio
Spain, Madrid
Universidad Complutense de Madrid
Mertens, Gerhard
Belgium, Edegem
Universitair Ziekenhuis Antwerpen
Parson, Walther
Austria, Innsbruck
Medizinische Universitat Innsbruck
Perone, Carlos
Brazil, Belo Horizonte
Universidade Federal de Minas Gerais
Prieto, L.
Spain, Alcala de Henares
Universidad de Alcalá
Takeshita, Haruo
Japan, Matsue
Shimane University
Rangel-Villalobos, Héctor
Mexico, Guadalajara
Universidad de Guadalajara
Zeng, Zhaoshu
China, Zhengzhou
Zhengzhou University
Zhivotovsky, Lev A.
Russian Federation, Moscow
Vavilov Institute of General Genetics, Russian Academy of Sciences
Camacho, Rui Carlos
Portugal, Porto
Universidade do Porto
Fonseca, Nuno A.
Portugal, Porto
Universidade do Porto
Statistics
Citations: 45
Authors: 24
Affiliations: 22
Identifiers
Doi:
10.1007/s00414-010-0472-2
ISSN:
09379827
e-ISSN:
14371596
Research Areas
Genetics And Genomics
Study Design
Cross Sectional Study