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AFRICAN RESEARCH NEXUS

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medicine

Imipenem resistance in Salmonella enterica serovar Wien related to porin loss and CMY-4 β-lactamase production

Antimicrobial Agents and Chemotherapy, Volume 47, No. 3, Year 2003

1Two multidrug-resistant Salmonella enterica serovar Wien strains (SW468 and SW1107) were isolated in 2001 in Tunis. Both strains produced the β-lactamases TEM-1, SHV-2a, and CMY-4, whereas strain SW1107 also produced the β-lactamase CTX-M-3. The imipenem-resistant strain (SW468) was totally devoid of the OmpF-immunorelated porin. Imipenem resistance was shown as being related to porin loss and CMY-4 β-lactamase production.
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Citations: 99
Authors: 7
Affiliations: 4
Research Areas
Infectious Diseases