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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Capsule homology does not increase the frequency of transformation of linked penicillin binding proteins PBP 1a and PBP 2x in Streptococcus pneumoniae
Antimicrobial Agents and Chemotherapy, Volume 49, No. 4, Year 2005
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Description
Penicillin resistance is mainly confined to a limited number of Streptococcus pneumoniae serotypes. Given linkage between the capsular biosynthesis locus and two penicillin binding proteins, we tested whether capsule homology increases transformation rates of penicillin resistance. Transformation rates in homologous donor-recipient pairs were no higher than expected, falsifying this hypothesis. Copyright © 2005, American Society for Microbiology. All Rights Reserved.
Authors & Co-Authors
Trzciñski, Krzysztof
United States, Boston
Harvard T.h. Chan School of Public Health
MacNeil, Adam
United States, Boston
Harvard T.h. Chan School of Public Health
Klugman, K. P.
United States, Atlanta
Emory University
Lipsitch, Marc
United States, Boston
Harvard T.h. Chan School of Public Health
Statistics
Citations: 2
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1128/AAC.49.4.1591-1592.2005
ISSN:
00664804