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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
DAMPD: A manually curated antimicrobial peptide database
Nucleic Acids Research, Volume 40, No. D1, Year 2012
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Description
The demand for antimicrobial peptides (AMPs) is rising because of the increased occurrence of pathogens that are tolerant or resistant to conventional antibiotics. Since naturally occurring AMPs could serve as templates for the development of new anti-infectious agents to which pathogens are not resistant, a resource that contains relevant information on AMP is of great interest. To that extent, we developed the Dragon Antimicrobial Peptide Database (DAMPD, http://apps.sanbi.ac.za/dampd) that contains 1232 manually curated AMPs. DAMPD is an update and a replacement of the ANTIMIC database. In DAMPD an integrated interface allows in a simple fashion querying based on taxonomy, species, AMP family, citation, keywords and a combination of search terms and fields (Advanced Search). A number of tools such as Blast, ClustalW, HMMER, Hydrocalculator, SignalP, AMP predictor, as well as a number of other resources that provide additional information about the results are also provided and integrated into DAMPD to augment biological analysis of AMPs. © The Author(s) 2011. Published by Oxford University Press.
Authors & Co-Authors
Sundararajan, Vijayaraghava Seshadri
South Africa, Bellville
University of the Western Cape
Singapore, Singapore City
School of Computer Science and Engineering
Gabere, Musa Nur
South Africa, Bellville
University of the Western Cape
Pretorius, Ashley
South Africa, Bellville
University of the Western Cape
Adam, Saleem
South Africa, Bellville
University of the Western Cape
Christoffels, Alan G.
South Africa, Bellville
University of the Western Cape
Lehvas̈laiho, Minna H.
Saudi Arabia, Thuwal
King Abdullah University of Science and Technology
Archer, John A.C.
Saudi Arabia, Thuwal
King Abdullah University of Science and Technology
Bajic, Vladimir B.
Saudi Arabia, Thuwal
King Abdullah University of Science and Technology
Statistics
Citations: 101
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.1093/nar/gkr1063
ISSN:
03051048
e-ISSN:
13624962