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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Schistosoma mansoni morbidity among adults in two villages along Lake Victoria shores in Mwanza District, Tanzania
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 102, No. 6, Year 2008
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Description
The study aimed to describe morbidity patterns due to intestinal schistosomiasis in adults living in two villages along the southern shores of Lake Victoria, Mwanza District, Tanzania. Nine hundred and fifty persons from Msozi and 497 from Sangabuye, aged between 14 and 87 years, were examined by abdominal ultrasound according to the Niamey protocol. Liver image patterns (LIP) A and B were considered normal and C-F as distinct periportal fibrosis (PPF). The frequency of PPF was higher in Msozi (41.5%) than in Sangabuye (16.7%) (P < 0.001) and was associated with high prevalence and intensity of Schistosoma mansoni infection. PPF was shown to be more common in males than females. Abnormal increase of segmental branch wall thickness (SBWT) and dilated portal vein diameter (PVD) were also more common among males than females. Hepatomegaly and splenomegaly were frequently encountered in both villages. The LIPs were positively correlated to size of SBWT and PVD but not to size of left liver lobe or spleen. In the study communities the risk of developing PPF differed greatly among individuals depending on various risk factors especially alcohol consumption. © 2008 Royal Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Malenganisho, Wabyahe
Tanzania, Tanga
National Institute for Medical Research Tanga
Magnussen, Pascal
Denmark, Copenhagen
Dbl -center for Health Research and Development
Friis, Henrik M.U.
Denmark, Copenhagen
Københavns Universitet
Siza, Julius E.
Tanzania, Tanga
National Institute for Medical Research Tanga
Kaatano, Godfrey M.
Tanzania, Tanga
National Institute for Medical Research Tanga
Temu, Mansuet M.
Tanzania, Tanga
National Institute for Medical Research Tanga
Vennervald, Birgitte Jyding
Denmark, Copenhagen
Dbl -center for Health Research and Development
Statistics
Citations: 56
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/j.trstmh.2008.03.006
ISSN:
00359203
Research Areas
Health System And Policy
Infectious Diseases
Substance Abuse
Study Design
Cross Sectional Study
Study Locations
Tanzania
Participants Gender
Female