Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

biochemistry, genetics and molecular biology

Extrachromosomal Amplification of Human Papillomavirus Episomes Is a Mechanism of Cervical Carcinogenesis

Cancer research, Volume 83, No. 11, Year 2023

SIGNIFICANCE: Multimers of the HPV genome are generated in cervical tumors replicating as extrachromosomal episomes, which is associated with deletion and rearrangement of the HPV genome and provides a mechanism for oncogenesis without integration.

Statistics
Citations: 13
Authors: 13
Affiliations: 5
Identifiers
Doi: 10.1158/0008-5472.CAN-22-3030
e-ISSN: 15387445
Research Areas
Cancer

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