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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Early epidemiological investigations: World Health Organization UNITY protocols provide a standardized and timely international investigation framework during the COVID-19 pandemic
Influenza and other Respiratory Viruses, Volume 16, No. 1, Year 2022
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Description
Background: The declaration of Coronavirus disease 2019 (COVID-19) as a Public Health Emergency of International Concern (PHEIC) on 30 January 2020 required rapid implementation of early investigations to inform appropriate national and global public health actions. Methods: The suite of existing pandemic preparedness generic epidemiological early investigation protocols was rapidly adapted for COVID-19, branded the ‘UNITY studies’ and promoted globally for the implementation of standardized and quality studies. Ten protocols were developed investigating household (HH) transmission, the first few cases (FFX), population seroprevalence (SEROPREV), health facilities transmission (n = 2), vaccine effectiveness (n = 2), pregnancy outcomes and transmission, school transmission, and surface contamination. Implementation was supported by WHO and its partners globally, with emphasis to support building surveillance and research capacities in low- and middle-income countries (LMIC). Results: WHO generic protocols were rapidly developed and published on the WHO website, 5/10 protocols within the first 3 months of the response. As of 30 June 2021, 172 investigations were implemented by 97 countries, of which 62 (64%) were LMIC. The majority of countries implemented population seroprevalence (71 countries) and first few cases/household transmission (37 countries) studies. Conclusion: The widespread adoption of UNITY protocols across all WHO regions indicates that they addressed subnational and national needs to support local public health decision-making to prevent and control the pandemic. © 2021 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd.
Authors & Co-Authors
Bergeri, Isabel
Switzerland, Geneva
Organisation Mondiale de la Santé
Lewis, Hannah Catherine
Switzerland, Geneva
Organisation Mondiale de la Santé
Subissi, Lorenzo
Switzerland, Geneva
Organisation Mondiale de la Santé
Valenciano, Marta
Switzerland, Geneva
Organisation Mondiale de la Santé
France, Paris
Epiconcept Sas
Omolade Abejirinde, Ibukun Oluwa
Switzerland, Geneva
Organisation Mondiale de la Santé
Simniceanu, Alice
Switzerland, Geneva
Organisation Mondiale de la Santé
Cassini, Alessandro
Switzerland, Geneva
Organisation Mondiale de la Santé
Grant, Rebecca L.
Switzerland, Geneva
Organisation Mondiale de la Santé
Vicari, Andrea S.
United States, Washington, D.c.
Pan American Health Organization
Al-Ariqi, Lubna
Switzerland, Geneva
Organisation Mondiale de la Santé
Wijesinghe, Pushpa Ranjan
Switzerland, Geneva
Organisation Mondiale de la Santé
Rajatonirina, Soatiana Cathycia
Congo, Brazzaville
World Health Organization Regional Office for Africa Congo
Okeibunor, Joseph Chukwudi
Congo, Brazzaville
World Health Organization Regional Office for Africa Congo
Le, Linh Vi N.
Switzerland, Geneva
Organisation Mondiale de la Santé
Katz, Mark A.
Switzerland, Geneva
Organisation Mondiale de la Santé
Vaughan, Aisling M.
Switzerland, Geneva
Organisation Mondiale de la Santé
Jorgensen, Pernille Knøs
Switzerland, Geneva
Organisation Mondiale de la Santé
Freidl, Gudrun Stephanie
Switzerland, Geneva
Organisation Mondiale de la Santé
Pebody, Richard G.
Switzerland, Geneva
Organisation Mondiale de la Santé
van Kerkhove, Maria D.
Switzerland, Geneva
Organisation Mondiale de la Santé
Statistics
Citations: 46
Authors: 20
Affiliations: 4
Identifiers
Doi:
10.1111/irv.12915
ISSN:
17502640
Research Areas
Covid
Maternal And Child Health
Sexual And Reproductive Health
Study Design
Cross Sectional Study