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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Patterns of hepatocellular carcinoma incidence in Egypt from a population-based cancer registry
Hepatology Research, Volume 38, No. 5, Year 2008
Notification
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Description
Aim: Hepatocellular carcinoma (HCC) is increasing worldwide, and is frequently attributed to rising rates of hepatitis C virus infection and interactions between viral and environmental risk factors. Because of Egypt's unique risk factor profile, we analyzed data from the Gharbiah Population-Based Cancer Registry for the period 1999-2003 to characterize demographic and geographic patterns of cases in this province. Methods: We calculated age- and sex-specific and age- and sex-standardized HCC incidence rates for the eight districts in Gharbiah. We also compared rates from Gharbiah with the USA (US Surveillance Epidemiology and End Results [SEER]database). Results: The analysis revealed a higher incidence in males than in females, significant geographic variations among districts, and a higher incidence in Gharbiah than that reported by SEER. Conclusion: The findings of this study document the heterogeneous distribution of HCC at regional and international levels. This population-based registry offers the opportunity for careful representative studies of various etiologies, particularly infectious and/or environmental factors that may contribute to risk. © 2007 The Japan Society of Hepatology.
Authors & Co-Authors
Lehman, Elizabeth M.
United States, Ann Arbor
University of Michigan, Ann Arbor
Soliman, Amr S.
United States, Ann Arbor
University of Michigan, Ann Arbor
Ismail, Kadry
Egypt, Tanta
Gharbiah Population-based Cancer Registry
Hablas, Ahmed
Egypt, Tanta
Gharbiah Population-based Cancer Registry
Seifeldin, Ibrahim A.
Egypt, Tanta
Gharbiah Population-based Cancer Registry
Ramadan, Mohammed
Egypt, Tanta
Gharbiah Population-based Cancer Registry
El-Hamzawy, Hesham
Egypt, Tanta
Gharbiah Population-based Cancer Registry
Shoushtari, Christiana S.
United States, Ann Arbor
University of Michigan, Ann Arbor
Wilson, Mark Lee
United States, Ann Arbor
University of Michigan, Ann Arbor
Statistics
Citations: 91
Authors: 9
Affiliations: 2
Identifiers
Doi:
10.1111/j.1872-034X.2007.00299.x
ISSN:
13866346
Research Areas
Cancer
Infectious Diseases
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Egypt
Participants Gender
Female