Publication Details

AFRICAN RESEARCH NEXUS

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biochemistry, genetics and molecular biology

Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis

Tetrahedron Letters, Volume 40, No. 5, Year 1999

Halitulin (2), a novel bisquinolinylpyrrole has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated mainly on the basis of spectroscopic data as well as chemical modifications. Halitulin was found to be cytotoxic against several tumor cells: P-388, A-549, HT-29 and MEL-28 in concentrations of 12-25 ng/ml.

Statistics
Citations: 70
Authors: 4
Affiliations: 3
Identifiers
Doi: 10.1016/S0040-4039(98)02467-8
ISSN: 00404039
Research Areas
Cancer

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