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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Role of oesophageal cooling in the prevention of oesophageal injury in atrial fibrillation catheter ablation: a systematic review and meta-analysis of randomized controlled trials
Europace, Volume 25, No. 5, Year 2023
Notification
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Description
Aims To evaluate the efficacy of oesophageal cooling in the prevention of oesophageal injury in patients undergoing atrial fibrillation (AF) catheter ablation. Methods Comprehensive search of MEDLINE, EMBASE, and Cochrane databases through April 2022 for randomized controlled trials and results (RCTs) evaluating the role of oesophageal cooling compared with control in the prevention of oesophageal injury during AF catheter ablation. The study primary outcome was the incidence of any oesophageal injury. The meta-analysis included 4 RCTs with a total of 294 patients. There was no difference in the incidence of any oesophageal injury between oesophageal cooling and control [15% vs. 19%; relative risk (RR) 0.86; 95% confidence interval (CI) 0.31–2.41]. Compared with control, oesophageal cooling showed lower risk of severe oesophageal injury (1.5% vs. 9%; RR 0.21; 95% CI 0.05–0.80). There were no significant differences among the two groups in mild to moderate oesophageal injury (13.6% vs. 12.1%; RR 1.09; 95% CI 0.28–4.23), procedure duration [standardized mean difference (SMD) −0.03; 95% CI −0.36–0.30], posterior wall radiofrequency (RF) time (SMD 0.27; 95% CI −0.04–0.58), total RF time (SMD −0.50; 95% CI −1.15–0.16), acute reconnection incidence (RR 0.93; 95% CI 0.02–36.34), and ablation index (SMD 0.16; 95% CI −0.33–0.66). Conclusion Among patients undergoing AF catheter ablation, oesophageal cooling did not reduce the overall risk of any oesophageal injury compared with control. Oesophageal cooling might shift the severity of oesophageal injuries to less severe injuries. Further studies should evaluate the long-term effects after oesophageal cooling during AF catheter ablation. © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.
Authors & Co-Authors
Hamed, Mohamed
United States, Boca Raton
Florida Atlantic University
Elseidy, Sheref Abdelgawad Hassan
United States, Rochester
Rochester General Hospital
Abdelazeem, Mohamed A.
United States, Brighton
St. Elizabeth's Medical Center
Morcos, Ramez
United States, Boca Raton
Florida Atlantic University
Sammour, Yasser M.
United States, Houston
Houston Methodist Hospital
Barakat, Amr F.
United States, Pittsburgh
University of Pittsburgh
Khalife, Wissam I.
United States, Galveston
The University of Texas Medical Branch at Galveston
Mamas, Mamas Andreas
United Kingdom, Keele
Keele University
Elbadawi, Ayman
United States, Dallas
Ut Southwestern Medical Center
Statistics
Citations: 2
Authors: 9
Affiliations: 9
Identifiers
Doi:
10.1093/europace/euad080
ISSN:
10995129
Research Areas
Violence And Injury
Study Design
Randomised Control Trial
Cohort Study
Study Approach
Systematic review