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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
PROSPECTIVE CONTROLLED TRIAL OF TRANSHEPATIC BILIARY ENDOPROSTHESIS VERSUS BYPASS SURGERY FOR INCURABLE CARCINOMA OF HEAD OF PANCREAS
The Lancet, Volume 327, No. 8472, Year 1986
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Description
53 patients with obstructive jaundice due to incurable carcinoma of the head of the pancreas were randomly allocated to percutaneous transhepatic placement of a permanent biliary endoprosthesis (PTE) or bypass surgery. After exclusions 25 patients in each group were treated. Technical success was achieved in 21 patients (84%) in the PTE group and 19 (76%) in the surgery group. The incidence of postprocedural complications (PTE 7, surgery 8) and 30-day mortality (PTE 2, surgery 5) were similar. Recurrent jaundice occurred more often in the PTE (8/21) than the surgery group (3/19). Duodenal obstruction developed in 3 patients in the PTE group. Although the initial median postprocedural hospital stay was significantly shorter in the PTE than the surgery group, the difference was no longer significant when readmissions for blocked endoprosthesis and gastric outlet obstruction were taken into account. There was no difference in the median survival time in the two groups (PTE 19 weeks, surgery 15 weeks). © 1986.
Authors & Co-Authors
Bornman, Philippus C.
South Africa, Observatory
Groote Schuur Hospital
Tobias, Raymond
South Africa, Observatory
Groote Schuur Hospital
Harries-Jones, E. Philip
South Africa, Observatory
Groote Schuur Hospital
Stiegmann, Gregory Van
South Africa, Observatory
Groote Schuur Hospital
Terblanche, John T.
South Africa, Observatory
Groote Schuur Hospital
Statistics
Citations: 233
Authors: 5
Affiliations: 1
Identifiers
Doi:
10.1016/S0140-6736(86)90719-1
ISSN:
01406736
Research Areas
Cancer
Health System And Policy
Study Design
Cohort Study