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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Cardiometabolic risk and disease in Indigenous Australians: The heart of the heart study
International Journal of Cardiology, Volume 171, No. 3, Year 2014
Notification
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Description
Objectives This study assessed the burden and determinants of cardiovascular and metabolic risk in a community sample of high risk Indigenous Australians. Background Indigenous Australians are over-represented in the most disadvantaged strata of Australian society. The role of psychosocial and socioeconomic factors in patterning cardiometabolic disease in this population is unclear. Methods The Heart of the Heart Study was a cross sectional study of 436 Aboriginal adults from remote, urban and peri-urban communities around Alice Springs (Northern Territory, Australia). Participants underwent detailed assessments of socio-demographic, psychosocial, cardiovascular and metabolic status. Results Individuals with depression were twice as likely to have cardiovascular disease (OR 2.03; 1.07-3.88; p < 0.05). Chronic kidney disease (39.7%, 37.2% and 18.2%) and diabetes (28.4%, 34.0% and 19.2%) were more common in peri-urban and remote compared to urban communities. Cardiovascular disease did not vary across locations (p = 0.069), but coronary artery disease did (p = 0.035 for trend). Unemployed individuals were more likely to have cardiovascular disease (OR 2.32; 1.33-4.06; p < 0.001). Socioeconomic gradients in coronary artery disease, all cardiovascular disease and diabetes, as measured by income, operated differentially across locations (p for location/socioeconomic status interactions 0.002; 0.01 and 0.04 respectively). Conclusion Participants had high rates of pre-existing cardiovascular disease, diabetes and chronic kidney disease. Cardiovascular risk in these communities was associated with psychosocial factors and socioeconomic indicators. However, gradients operated differentially across location. These data provide a strong foundation for better understanding key drivers of increased levels of cardiovascular and other common forms of non-communicable disease in Indigenous people. © 2013 Elsevier Ireland Ltd.
Authors & Co-Authors
Brown, Alex D.H.
Australia, Melbourne
Baker Heart and Diabetes Institute
Australia, Adelaide
South Australian Health and Medical Research Institute
Carrington, Melinda J.
Australia, Melbourne
Baker Heart and Diabetes Institute
Lee, Geraldine Ann
Australia, Melbourne
Baker Heart and Diabetes Institute
Krum, Henry
Australia, Clayton
Monash University
Rowley, Kevin G.
Australia, Melbourne
University of Melbourne
Stewart, Simon D.
Australia, Melbourne
Baker Heart and Diabetes Institute
Statistics
Citations: 33
Authors: 6
Affiliations: 5
Identifiers
Doi:
10.1016/j.ijcard.2013.12.026
ISSN:
01675273
Research Areas
Mental Health
Noncommunicable Diseases
Study Design
Cross Sectional Study