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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The Mycetoma Knowledge Gap: Identification of Research Priorities
PLoS Neglected Tropical Diseases, Volume 8, No. 3, Article e2667, Year 2014
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Description
Mycetoma is a tropical disease which is caused by a taxonomically diverse range of actinomycetes (actinomycetoma) and fungi (eumycetoma). The disease was only recently listed by the World Health Organization (WHO) as a neglected tropical disease (NTD). This recognition is the direct result of a meeting held in Geneva on February 1, 2013, in which experts on the disease from around the world met to identify the key research priorities needed to combat mycetoma. The areas that need to be addressed are highlighted here. The initial priority is to establish the incidence and prevalence of the disease in regions where mycetoma is endemic, prior to determining the primary reservoirs of the predominant causal agents and their mode of transmission to susceptible individuals in order to establish novel interventions that will reduce the impact of the disease on individuals, families, and communities. Critically, economical, reliable, and effective methods are required to achieve early diagnosis of infections and consequential improved therapeutic outcomes. Molecular techniques and serological assays were considered the most promising in the development of novel diagnostic tools to be used in endemic settings. Improved strategies for treating eumycetoma and actinomycetoma are also considered. © 2014 van de Sande et al.
Authors & Co-Authors
van de Sande, Wendy W.J.
Netherlands, Rotterdam
Erasmus Mc
Maghoub, El Sheikh
Sudan, Khartoum
Khartoum University
Hassan Fahal, Ahmed Hassan
Sudan, Khartoum
Khartoum University
Goodfellow, Michael
United Kingdom, Newcastle
Newcastle University
Welsh, Oliverio
Mexico, Monterrey
Hospital Universitario Dr. Jose Eleuterio Gonzalez
Zijlstra, Eduard Evert
Netherlands, Rotterdam
Rotterdam Centre for Tropical Medicine
Statistics
Citations: 87
Authors: 6
Affiliations: 5
Identifiers
Doi:
10.1371/journal.pntd.0002667
ISSN:
19352727
e-ISSN:
19352735
Study Design
Cross Sectional Study
Cohort Study