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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Tropical spastic paraparesis in the seychelles islands: A clinical and case-control neuroepidemiologic study
Neurology, Volume 37, No. 8, Year 1987
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Description
We confirmed the occurrence of endemic tropical spastic paraparesis (TSP) in the Seychelles. Most patients (14/21) were low-income black women. Mean age at onset was 42.8 years (range, 20 to 65). In 62%, onset and progression were slow. Complete paralysis developed in 8/21 (38%) after an evolution of 2 to 15 years. All patients had bilateral pyramidal signs. Loss of vibratory perception occurred in 6/21 (28%). A case-control study of putative risk factors failed to show significant differences. The clinical and epidemiologic features of TSP in the Seychelles appear to be similar to those described in other tropical countries. © 1987 American Academy of Neurology.
Authors & Co-Authors
Román, Gustavo C.
United States, Lubbock
Ttuhsc School of Medicine, Lubbock
Spencer, P. S.
United States, New York
Albert Einstein College of Medicine of Yeshiva University
Schoenberg, Bruce S.
United States, Bethesda
National Institutes of Health Nih
Hugon, Jacques
France, Limoges
Chu de Limoges
Ludolph, Albert Christian
Germany, Munster
Universitätsklinikum Münster
Rodgers-Johnson, P.
United States, Bethesda
National Institute of Neurological Disorders and Stroke
Osuntokun, Benjamin O.
Nigeria, Ibadan
University College Hospital, Ibadan
Shamlaye, Conrad F.
Seychelles, Mahe
Ministry of Health Seychelles
Statistics
Citations: 46
Authors: 8
Affiliations: 8
Identifiers
Doi:
10.1212/wnl.37.8.1323
ISSN:
00283878
e-ISSN:
1526632X
Study Design
Case-Control Study
Study Locations
Seychelles
Participants Gender
Female