Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Timing of therapy for latent tuberculosis infection among immigrants presenting to a U.S. public health clinic: A retrospective study
BMC Public Health, Volume 8, Article 158, Year 2008
Notification
URL copied to clipboard!
Description
Background. In the U.S. more than half of incident tuberculosis (TB) cases occur in immigrants. Current guidelines recommend screening and treatment for latent TB infection (LTBI) within 5 years of arrival to the U.S. This study evaluates the timing of LTBI therapy among immigrants presenting for care to a public health TB clinic. Methods. Retrospective chart review of patients prescribed LTBI treatment based on medical records from Prince Georges County Health Department. Results. 1882 immigrants received LTBI therapy at Prince Georges County Health Department between 1999 and 2004. 417 of these patients were diagnosed with LTBI through contact investigations and were excluded from the analysis. Among the remaining 1465 individuals, median time from arrival to the U.S. until initiation of LTBI therapy was 5 months (range 0-42.4 years). 16% of all immigrants initiated therapy more than 5 years after arrival to the U.S. A logistic regression model using risks identified on univariate analysis revealed that referral for therapy by non-immigration proceedings was the strongest predictor of initiation of therapy more than 5 years after arrival to the U.S. Other factors associated with > 5 year U.S. residence prior to initiation of LTBI therapy included female gender (adjusted odds ratio (AOR) 1.8, 95% CI 1.2-2.6), age ≥ 35 (AOR = 4.1, 95% 2.5-6.6), and originating from Latin American and the Caribbean (AOR = 1.9, 95% CI 1.3-3.0). Conclusion. Foreign-born individuals who are not referred for LTBI therapy through immigration proceedings are less likely to receive LTBI therapy within 5 years of arrival to the U.S. These data highlight the need to explore other mechanisms for timely LTBI screening beyond services provided by immigration. © 2008 Page et al; licensee BioMed Central Ltd.
Authors & Co-Authors
Manabe, Yukari C.
United States, Baltimore
Johns Hopkins University
Cronin, Wendy A.
United States, Baltimore
Maryland State Department of Health and Mental Hygiene
Campbell, James D.
United States, Baltimore
University of Maryland, Baltimore Umb
Dorman, Susan E.
United States, Baltimore
Johns Hopkins University
Statistics
Citations: 3
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1186/1471-2458-8-158
ISSN:
14712458
Research Areas
Health System And Policy
Infectious Diseases
Study Design
Cohort Study
Case-Control Study
Participants Gender
Female