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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Medication use pattern and predictors of optimal therapy at discharge in 8176 patients with acute coronary syndrome from 6 Middle Eastern countries: Data from the gulf registry of acute coronary events
Angiology, Volume 62, No. 6, Year 2011
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Description
We evaluated the use of quadruple evidence-based medication (EBM) combination consisting of antiplatelet therapy, angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker, β-blocker, and lipid-lowering agent concurrently at discharge among patients (n = 8154) with acute coronary syndrome (ACS) in 6 Middle Eastern countries. In all, 49% of the patients received the quadruple EBM combination concurrently at discharge. An adjusted model demonstrated that old age, diabetes mellitus, hyperlipidemia, hypertension, ST-segment elevation myocardial infarction, cardiac catheterization, as well as cardiologists as care providers and hospitals with cardiac catheterization facilities were all positively correlated with the use of the quadruple EBM combination. However, patients with cardiogenic shock, renal impairment, higher risk score, congestive heart failure, recurrent ischemia, and those admitted to academic hospitals were negatively correlated with the use of the quadruple EBM combination. Guideline adherence to the concurrent use of quadruple EBM combination in patients with ACS at discharge was suboptimal with wide disparity among the 6 countries. © 2011 The Author(s).
Authors & Co-Authors
Al-Zakwani, Ibrahim Saud
Oman, Muscat
Sultan Qaboos University
Oman, Muscat
Gulf Health Research
Zubaid, Mohammad
Kuwait, Kuwait City
Kuwait University
Panduranga, Prashanth
Oman, Muscat
Royal Hospital
Rashed, Wafa A.
Kuwait, Safat
Mubarak Al-kabeer Hospital
Sulaiman, Kadhim J.
Oman, Muscat
Royal Hospital
Al-Mahmeed, Wael Abdulrahman R.
United Arab Emirates, Abu Dhabi
Division of Cardiology
Al-Motarreb, Ahmed Lotf
Yemen, Sana'a
Al-thawra Hospital
Al Suwaidi, Jassim Mohd
Qatar, Doha
Hamad Medical Corporation
Amin, Haitham
Bahrain, West Riffa
Bahrain Defence Force Royal Medical Services
Statistics
Citations: 27
Authors: 9
Affiliations: 9
Identifiers
Doi:
10.1177/0003319710394163
ISSN:
00033197
e-ISSN:
19401574
Research Areas
Noncommunicable Diseases