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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
psychology
A Randomised-Controlled Trial of Vitamin D and Omega-3 Long Chain Polyunsaturated Fatty Acids in the Treatment of Core Symptoms of Autism Spectrum Disorder in Children
Journal of Autism and Developmental Disorders, Volume 49, No. 5, Year 2019
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Description
We evaluated the efficacy of vitamin D (VID), omega-3 long chain polyunsaturated fatty acids (omega-3 LCPUFA, OM), or both (VIDOM) on core symptoms of ASD. New Zealand children with ASD (n = 73; aged 2.5–8.0 years) received daily 2000 IU vitamin D 3 , 722 mg docosahexaenoic acid, both, or placebo. Outcome measures were Social Responsiveness Scale (SRS) and Sensory Processing Measure (SPM). Of 42 outcome measures comparisons (interventions vs. placebo), two showed greater improvements (P = 0.03, OM and VIDOM for SRS-social awareness) and four showed trends for greater improvements (P < 0.1, VIDOM for SRS-social communicative functioning, OM for SRS-total, VIDOM for SPM-taste/smell and OM for SPM-balance/motion). Omega-3 LCPUFA with and without vitamin D may improve some core symptoms of ASD but no definitive conclusions can be made. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
Authors & Co-Authors
Kruger, Marlena Cathorina
New Zealand, Palmerston North
Massey University
Stonehouse, Welma
Australia, Canberra
Commonwealth Scientific and Industrial Research Organisation
Camargo, Carlos Arturo
United States, Boston
Harvard Medical School
Statistics
Citations: 33
Authors: 3
Affiliations: 5
Identifiers
Doi:
10.1007/s10803-018-3860-y
ISSN:
01623257
Research Areas
Disability
Maternal And Child Health