Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Global variation in the pattern of differentiated thyroid cancer
American Journal of Surgery, Volume 200, No. 4, Year 2010
Notification
URL copied to clipboard!
Description
Background: The prevalence of differentiated thyroid cancer (DTC) is increasing worldwide. Iodine deficiency is a risk factor for follicular thyroid cancer (FTC). We compared DTC subtypes in an iodine-deficient country with a developed country. Methods: A retrospective review of thyroid cancer at tertiary centers in West Africa and the United States. All patients diagnosed with thyroid cancer from 1980 to 2004 were retrieved from the West African Center's Cancer Registry Database. The study period was divided into two groups: 1980 to 1989 and 1990 to 2004. In the American center, a review of patients undergoing surgery for thyroid cancer from 1997 to 2008 was performed. Results: At the African institution, 322 patients underwent thyroidectomy for cancer from 1980 to 2004. Overall, 31.5% had papillary thyroid cancer (PTC), and 30.3% had FTC. From 1980 to 1989, 27.3% had PTC and 35.8% had FTC. From 1990 to 2004, 35.7% had PTC and 24.8% had FTC. At the American institution, 105 patients underwent surgery for thyroid cancer from 1997 to 2008; 79% had PTC and 7.6% had FTC. Conclusions: FTC is still common in developing countries, whereas PTC is the predominant subtype in developed countries. Efforts to decrease iodine deficiency may improve outcomes by changing to a less aggressive subtype. © 2010 Elsevier Inc. All rights reserved.
Authors & Co-Authors
Woodruff, Stacey L.
United States, Richardson
The University of Texas at Dallas
Arowolo, Olukayode Adeolu
Nigeria, Ibadan
University College Hospital, Ibadan
Akute, Olusola O.
Nigeria, Ibadan
University College Hospital, Ibadan
Afolabi, Adefemi Oladiran
Nigeria, Ibadan
University College Hospital, Ibadan
Nwariaku, Fiemu E.
United States, Richardson
The University of Texas at Dallas
Statistics
Citations: 49
Authors: 5
Affiliations: 2
Identifiers
Doi:
10.1016/j.amjsurg.2010.03.009
Research Areas
Cancer
Health System And Policy
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Multi-countries