α-Glucosidase inhibitors from Millettia conraui

A new geranylated isoflavone, 7-O-geranyl-6-methoxypseudobaptigenin (1) was isolated from the stem barks of Millettia conraui, along with known compounds 5-methoxydurmillone (2), conrauinone A (3), β-amyrine (4), sitosterol (5), 3-O-β-D-glucopyranosyl sitosterol (6) and n-docosanol (7). Compounds 1 and 4 showed a significant α-glucosidase inhibitory activity. The structures of the compounds were determined by analysis of their spectroscopic data. © 2007 Pharmaceutical Society of Japan.