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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
ST2859 serogroup a meningococcal meningitis outbreak in Nouna Health District, Burkina Faso: A prospective study
Tropical Medicine and International Health, Volume 13, No. 6, Year 2008
Notification
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Description
We analysed cerebrospinal fluid samples from suspected meningitis cases in Nouna Health District, Burkina Faso, during the meningitis seasons of 2004-2006. Serogroup A ST2859 meningococci belonging to the ST5 clonal complex of subgroup III meningococci were the predominant causative agent. ST2859 bacteria were associated with focal outbreaks in the north of the district. While >10% of the population of an outbreak village carried ST2859, the population in the south of the district was predominantly colonised by serogroup Y ST4375 meningococci, which were associated with only sporadic cases of meningitis. Colonisation with the less virulent Y meningococci may interfere with the spread of the ST2859 to the south of the district, but there are concerns that this serogroup A clone may cause a third wave of subgroup III meningococcal disease in the African Meningitis Belt. © 2008 Blackwell Publishing Ltd.
Authors & Co-Authors
Sié, Alie
Burkina Faso, Nouna
Centre de Recherche en Sante de Nouna
Pflüger, Valentin P.
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Coulibaly, Boubacar
Burkina Faso, Nouna
Centre de Recherche en Sante de Nouna
Dangy, Jean Pierre
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Kapaun, Annette
Germany, Heidelberg
Universitätsklinikum Heidelberg
Junghanss, Thomas
Germany, Heidelberg
Universitätsklinikum Heidelberg
Pluschke, Gerd
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Leimkugel, Julia
Germany, Heidelberg
Universitätsklinikum Heidelberg
Statistics
Citations: 28
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.1111/j.1365-3156.2008.02056.x
ISSN:
13602276
e-ISSN:
13653156
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Burkina Faso