Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Antibacterial, antifungal and cytotoxic activities of two flavonoids from Retama raetam flowers
Molecules, Volume 17, No. 6, Year 2012
Notification
URL copied to clipboard!
Description
We have investigated the antibacterial, antifungal and cytotoxic activities of two flavonoids isolated from Retama raetam flowers using the disc diffusion and micro-dilution broth methods. The cytotoxic activity was tested against Hep-2 cells using the MTT assay. The compounds licoflavone C (1) and derrone (2) were active against Pseudomonas aeruginosa and Escherichia coli (7.81-15.62 μg/mL) and showed important antifungal activity. Strong antifungal activity against Candida species (7.81 μg/mL) was for example found with compound 2. The tested compounds also showed strong cytotoxicity against Hep-2 cells. These two compounds may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. © 2012 by the authors.
Authors & Co-Authors
Edziri, H.
Tunisia, Monastir
Faculté de Pharmacie de Monastir
Mastouri, Maha
Tunisia, Monastir
Chu Fattouma-bourguiba
Mahjoub, Mohamed Ali
Tunisia, Monastir
Faculté Des Sciences de Monastir
Mighri, Zine
Tunisia, Monastir
Chu Fattouma-bourguiba
Aouni, Mahjoub
Tunisia, Monastir
Faculté de Pharmacie de Monastir
Verschaeve, Luc
Belgium, Brussels
Scientific Institute of Public Health, Brussels
Belgium, Antwerpen
Universiteit Antwerpen
Statistics
Citations: 87
Authors: 6
Affiliations: 5
Identifiers
Doi:
10.3390/molecules17067284
e-ISSN:
14203049