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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Tuberculosis infection in Zambia: The association with relative wealth
American Journal of Tropical Medicine and Hygiene, Volume 80, No. 6, Year 2009
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Description
This study aimed to assess the association between household socioeconomic position and tuberculosis (TB) infection in two communities of Zambia. For this purpose we implemented a cross-sectional investigation, nested within a larger case control study. Infection was assessed using Quantiferon-TB Gold. A socioeconomic position index was constructed through principal component analysis combining data on human resources, food availability, housing quality, and access to services and infrastructures. In this study, higher socioeconomic position, rather than lower, was associated with significantly higher risk of TB infection. None of the traditional risk factors for TB infection mediated this association, suggesting that in these two communities TB transmission may occur through exposure to as yet undefined risk factors that are associated with higher socioeconomic position. Although further studies are needed, these results suggest emerging new patterns of TB transmission and a role of socioeconomic position on the risk of TB infection opposite to that expected. Copyright © 2009 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Boccia, Delia
Unknown Affiliation
Hargreaves, James R.
Unknown Affiliation
Ayles, Helen Mary
Unknown Affiliation
Fielding, Katherine Linda
Unknown Affiliation
Simwinga, M.
Unknown Affiliation
Godfrey-Faussett, P. D.
Unknown Affiliation
Statistics
Citations: 43
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.4269/ajtmh.2009.80.1004
ISSN:
00029637
Research Areas
Food Security
Health System And Policy
Infectious Diseases
Study Design
Cross Sectional Study
Case-Control Study
Study Locations
Zambia