Genetic environment of acquired blaACC-1 β-lactamase gene in Enterobacteriaceae isolates

We studied the genetic organization of blaACC-1 in 14 isolates of Enterobacteriaceae from France, Tunisia, and Germany. In a common ancestor, ISEcp1 was likely involved in the mobilization of this gene from the Hafnia alvei chromosome to a plasmid. Other genetic events involving insertion sequences (particularly IS26), transposons (particularly Tn1696), or sull-type integrons have occurred, leading to complex genetic environments. Copyright © 2006, American Society for Microbiology. All Rights Reserved.