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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
P-wave and QRS complex measurements in patients undergoing hemodialysis
Journal of Electrocardiology, Volume 41, No. 1, Year 2008
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Description
Hemodialysis (HD) has been associated with an increase in the amplitude of QRS complexes. Experience in a single patient with multiple measurements has shown that HD leads also to augmentation of P-wave amplitude. The objective of this investigation was to evaluate electrocardiogram (ECG) changes with HD in a cohort of patients undergoing this procedure with particular emphasis on the P-wave and QRS complex changes. The sum of amplitudes of P waves (ÓP) and QRS complexes (ÓQRS) in millimeters in the 12 leads of the ECG, along with a host of other ECG parameters, body weight, blood pressure, heart rate, electrolytes, and hemoglobin/hematocrit were measured before and immediately after HD in 47 patients. Hemodialysis resulted in a loss of a mean of 3 kg of weight and an increase in the ΣP, ΣQRS, mean QRS duration, maximum P-wave duration, and P-wave duration measured in lead II, whereas the changes in mean P-wave and corrected QT interval durations were not statistically significant. Percentage change (Δ%) in ΣP and ΣQRS correlated poorly with Δ% in electrolytes, hematocrit, blood pressure, heart rate, and weight. Values for ΣP and ΣQRS vs weight were r = 0.105, P = .48 and r = 0.09, P = .51, respectively. The Δ% in ΣP correlated well with Δ% in ΣQRS (r = 0.42, P = .003). Alterations in P-wave amplitudes and duration commensurate with the ones affecting the corresponding QRS complexes occur in patients undergoing HD and indicate that evaluation of measurements in serial ECGs should take this into account. The mechanisms of these phenomena continue to be elusive, and whether they represent cardiac and/or extracardiac influences has not as yet been unraveled. © 2008 Elsevier Inc. All rights reserved.
Authors & Co-Authors
Drighil, Abdenasser A.
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Madias, John E.
United States, New York
New York University
United States, Elmhurst
Elmhurst Hospital Center
Yazidi, Asma Alaoui
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Bennani, Mohammed
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Bennis, Ahmed
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Ramdan, Beenyouness
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Tahiri, Azzeddine
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Statistics
Citations: 28
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/j.jelectrocard.2006.03.002
ISSN:
00220736
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Cohort Study