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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Intrasaccular flow disruption for ruptured aneurysms: An international multicenter study
Journal of NeuroInterventional Surgery, Volume 15, No. 9, Year 2023
Notification
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Description
Background The Woven EndoBridge (WEB) device is a novel intrasaccular flow disruptor tailored for bifurcation aneurysms. We aim to describe the degree of aneurysm occlusion at the latest follow-up, and the rate of complications of aneurysms treated with the WEB device stratified according to rupture status. Methods Our data were taken from the WorldWideWeb Consortium, an international multicenter cohort including patients treated with the WEB device. Aneurysms were classified into two groups: ruptured and unruptured. We compared clinical and radiologic outcomes of both groups. Propensity score matching (PSM) was done to match according to age, gender, bifurcation, location, prior treatment, neck, height, dome width, daughter sac, incorporated branch, pretreatment antiplatelets, and last imaging follow-up. Results The study included 676 patients with 691 intracranial aneurysms (529 unruptured and 162 ruptured) treated with the WEB device. The PSM analysis had 55 pairs. In both the unmatched (85.8% vs 84.3%, p=0.692) and matched (94.4% vs 83.3%, p=0.066) cohorts there was no significant difference in the adequate occlusion rate at the last follow-up. Likewise, there were no significant differences in both ischemic and hemorrhagic complications between the two groups. There was no documented aneurysm rebleeding after WEB device implantation. Conclusion There was no significant difference in both the radiologic outcomes and complications between unruptured and ruptured aneurysms. Our findings support the feasibility of treatment of ruptured aneurysms with the WEB device. © Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.
Authors & Co-Authors
Diestro, Jose Danilo Bengzon
Canada, Toronto
University of Toronto
Dibas, Mahmoud
United States, Boston
Brigham and Women's Hospital
Regenhardt, Robert W.
United States, Boston
Massachusetts General Hospital
Vranic, Justin E.
United States, Boston
Massachusetts General Hospital
Renieri, Leonardo
Italy, Florence
Azienda Ospedaliera Careggi
Shotar, Eimad
France, Paris
Sorbonne Université
Premat, Kévin
France, Paris
Sorbonne Université
El Naamani, Kareem
United States, Philadelphia
Thomas Jefferson University
Saliou, Guillaume
Switzerland, Lausanne
Centre Hospitalier Universitaire Vaudois
Möhlenbruch, Markus Alfred
Germany, Heidelberg
Universität Heidelberg
Tutino, Vincent Matthew
United States, Buffalo
University at Buffalo, the State University of new York
Ghozy, Sherief A.
United States, Rochester
Mayo Clinic
Alotaibi, Naif M.
United States, Boston
Massachusetts General Hospital
Rabinov, James David
United States, Boston
Massachusetts General Hospital
Piano, Mariangela G.
Italy, Milan
Asst Grande Ospedale Metropolitano Niguarda
Kühn, Anna Luisa
United States, Worcester
Umass Memorial Medical Center
Starke, Robert M.
United States, Coral Gables
University of Miami
Hassan, Ameer E.
Unknown Affiliation
Psychogios, Marios Nikos
Switzerland, Basel
Universitätsspital Basel
Spears, Julian
Canada, Toronto
University of Toronto
Salem, Mohamed M.
United States, Philadelphia
University of Pennsylvania
Burkhardt, Jan Karl
United States, Philadelphia
University of Pennsylvania
Panni, Pietro
Italy, Milan
Irccs Ospedale San Raffaele
Puri, Ajit S.
United States, Worcester
Umass Memorial Medical Center
Pero, Guglielmo Carlo
Italy, Milan
Asst Grande Ospedale Metropolitano Niguarda
Griessenauer, Christoph Johannes
Austria, Salzburg
Paracelsus Medizinische Privatuniversitat
Asadi, Hamed
Australia, Melbourne
Austin Health
Siddiqui, Adnan Hussain
United States, Buffalo
University at Buffalo, the State University of new York
Ducruet, A. F. F.
United States, Phoenix
Barrow Neurological Institute
Albuquerque, Felipe C.A.
United States, Phoenix
Barrow Neurological Institute
Du, Rose
United States, Boston
Brigham and Women's Hospital
Kan, Peter Tze Man
United States, Houston
Baylor College of Medicine
Lylyk, Pedro L.
Unknown Affiliation
Stapleton, Christopher J.
United States, Boston
Massachusetts General Hospital
Jabbour, P. M.
United States, Philadelphia
Thomas Jefferson University
Tjoumakaris, Stavropoula I.
United States, Philadelphia
Thomas Jefferson University
Clareņcon, Fréd́eric
France, Paris
Hôpital Universitaire Pitié Salpêtrière
Ali Aziz-Sultan, Mohammad Ali
United States, Boston
Brigham and Women's Hospital
Cognard, Christophe H.
France, Toulouse
Chu de Toulouse
Patel, Aman B.
United States, Boston
Massachusetts General Hospital
Dmytriw, Adam Andrew
United States, Boston
Brigham and Women's Hospital
United States, Boston
Massachusetts General Hospital
Statistics
Citations: 3
Authors: 41
Affiliations: 32
Identifiers
Doi:
10.1136/jnis-2022-019153
ISSN:
17598478
Study Design
Cohort Study
Case-Control Study