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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Defining core patient descriptors for perforated peptic ulcer research: International Delphi
British Journal of Surgery, Volume 109, No. 7, Year 2022
Notification
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Description
Background: Perforated peptic ulcer (PPU) remains a common condition globally with significant morbidity and mortality. Previous work has demonstrated variation in reporting of patient characteristics in PPU studies, making comparison of studies and outcomes difficult. The aim of this study was to standardize the reporting of patient characteristics, by creating a core descriptor set (CDS) of important descriptors that should be consistently reported in PPU research. Methods: Candidate descriptors were identified through systematic review and stakeholder proposals. An international Delphi exercise involving three survey rounds was undertaken to obtain consensus on key patient characteristics for future research. Participants rated items on a scale of 1-9 with respect to their importance. Items meeting a predetermined threshold (rated 7-9 by over 70 per cent of stakeholders) were included in the final set and ratified at a consensus meeting. Feedback was provided between rounds to allow refinement of ratings. Results: Some 116 clinicians were recruited from 29 countries. A total of 63 descriptors were longlisted from the literature, and 27 were proposed by stakeholders. After three survey rounds and a consensus meeting, 27 descriptors were included in the CDS. These covered demographic variables and co-morbidities, risk factors for PPU, presentation and pathway factors, need for organ support, biochemical parameters, prognostic tools, perforation details, and surgical history. Conclusion: This study defines the core descriptive items for PPU research, which will allow more robust synthesis of studies. © 2022 The Author(s). Published by Oxford University Press on behalf of BJS Society Ltd. All rights reserved.
Authors & Co-Authors
MacUtkiewicz, Christian
United Kingdom, Sheffield
The University of Sheffield
Griffiths, Ewen A.
United Kingdom, Sheffield
The University of Sheffield
Catena, Fausto
United Kingdom, Sheffield
The University of Sheffield
Coccolini, Federico
United Kingdom, Sheffield
The University of Sheffield
Toogood, G. John
United Kingdom, Sheffield
The University of Sheffield
Sartelli, Massimo
United Kingdom, Sheffield
The University of Sheffield
Blencowe, Natalie S.
United Kingdom, Sheffield
The University of Sheffield
Lee, Matthew J.
United Kingdom, Sheffield
The University of Sheffield
Drake, Thomas M.
United Kingdom, Sheffield
The University of Sheffield
Gachabayov, Mahir
United Kingdom, Sheffield
The University of Sheffield
Ioannidis, Orestis M.
United Kingdom, Sheffield
The University of Sheffield
Lostoridis, Eftychios
United Kingdom, Sheffield
The University of Sheffield
Mehraj, Asif
United Kingdom, Sheffield
The University of Sheffield
Negoi, Ionut
United Kingdom, Sheffield
The University of Sheffield
Pata, Francesco
United Kingdom, Sheffield
The University of Sheffield
Demirli Atlcl, Semra
United Kingdom, Sheffield
The University of Sheffield
Bains, Lovenish
United Kingdom, Sheffield
The University of Sheffield
Bandyopadhyay, Samik Kumar
United Kingdom, Sheffield
The University of Sheffield
Baraket, Oussama
United Kingdom, Sheffield
The University of Sheffield
Buonomo, Luis Antonio
United Kingdom, Sheffield
The University of Sheffield
Ceresoli, Marco
United Kingdom, Sheffield
The University of Sheffield
Chapman, Stephen J.
United Kingdom, Sheffield
The University of Sheffield
Cillara, Nicola
United Kingdom, Sheffield
The University of Sheffield
Çolak, Elif F.
United Kingdom, Sheffield
The University of Sheffield
Demetrashvili, Zaza M.
United Kingdom, Sheffield
The University of Sheffield
Di Carlo, Isidoro
United Kingdom, Sheffield
The University of Sheffield
Duff, Sarah Elizabeth
United Kingdom, Sheffield
The University of Sheffield
El Zalabany, Tamer
United Kingdom, Sheffield
The University of Sheffield
Ewnte, Biniam
United Kingdom, Sheffield
The University of Sheffield
Fraga, Gustavo Pereira
United Kingdom, Sheffield
The University of Sheffield
Giuffrida, Mario C.
United Kingdom, Sheffield
The University of Sheffield
Glasbey, James C.
United Kingdom, Sheffield
The University of Sheffield
Isik, Arda A.
United Kingdom, Sheffield
The University of Sheffield
Kechagias, Aristotelis
United Kingdom, Sheffield
The University of Sheffield
Kessel, Boris Juli
United Kingdom, Sheffield
The University of Sheffield
Khokha, Vladimir M.
United Kingdom, Sheffield
The University of Sheffield
Kong, Victor Yeewai
United Kingdom, Sheffield
The University of Sheffield
Litvin, A. A.
United Kingdom, Sheffield
The University of Sheffield
Marinis, A. D.
United Kingdom, Sheffield
The University of Sheffield
Martínez-Pérez, Aleix
United Kingdom, Sheffield
The University of Sheffield
Monzon, Barbaro I.
United Kingdom, Sheffield
The University of Sheffield
Nita, Gabriela Elisa
United Kingdom, Sheffield
The University of Sheffield
Perra, Teresa
United Kingdom, Sheffield
The University of Sheffield
Perrone, Gennaro
United Kingdom, Sheffield
The University of Sheffield
Porcu, Alberto
United Kingdom, Sheffield
The University of Sheffield
Poškus, Tomas
United Kingdom, Sheffield
The University of Sheffield
Sall, Ibrahima
United Kingdom, Sheffield
The University of Sheffield
Slavchev, M.
United Kingdom, Sheffield
The University of Sheffield
Tarasconi, Antonio
United Kingdom, Sheffield
The University of Sheffield
Tolonen, Matti
United Kingdom, Sheffield
The University of Sheffield
Toro, Adriana
United Kingdom, Sheffield
The University of Sheffield
Venn, Mary L.
United Kingdom, Sheffield
The University of Sheffield
Zakaria, Andee Dzulkarnaen
United Kingdom, Sheffield
The University of Sheffield
Statistics
Authors: 53
Affiliations: 1
Identifiers
Doi:
10.1093/bjs/znac096
ISSN:
00071323
Research Areas
Health System And Policy
Study Design
Cross Sectional Study
Study Approach
Quantitative
Systematic review