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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Bacteriological aspects of osteitis in a university hospital
Medecine et Maladies Infectieuses, Volume 37, No. 12, Year 2007
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Description
Introduction: The aim, of our retrospective study, was to determine the epidemiological and susceptibility profile of bacterial osteitis isolates in the Rabat Mohammed V Military Hospital, to optimize the probabilistic antibiotherapy. Materials and methods: A study was made from August 2004 to December 2005. All the positive specimen for the etiologic diagnosis of osteitis and osteoarthritis were included. Results: During this period, 85 osteitis cases were documented. 123 isolates were collected. 31 cases of osteitis allowed for the isolation of at least 2 bacteria (36.5%). The Gram positive cocci rate was 54.5%, the Gram negative bacilli rate 39.8%, and the Gram positive bacilli rate 5.7%. The distribution by groups was staphylococcus spp 46.4%, enterobacteriaceae 25.2% and non-fermenting Gram negative bacilli 12.9%. The most frequently isolated species were Staphylococcus aureus (23,6%) followed by Pseudomonas aeruginosa (8.9%), and Klebsiella pneumoniae (5.7%). All the S. aureus isolates were susceptible to oxacillin and 30.8% of the coagulase negative staphylococci were resistant. The enterobacteriaceae resistance rates were 64.5% for clavulanic acid-amoxicillin and 16% for third generation cephalosporin and ciprofloxacin. The non-fermenting Gram negative bacilli resistance rate was 37.5% for ceftazidim, 62.5% for ticarcillin, and 12.5% for imipenem. Conclusion: Our results show the potential efficient therapy for community osteitis, using the traditional association: methicillin-aminosides and oral relay with fluoroquinolones. In nosocomial osteitis, the antibiotherapy must be modulated according to the identification and an antibiogram. © 2007 Elsevier Masson SAS. All rights reserved.
Authors & Co-Authors
Élouennass, Mostafa
Morocco, Agdal Rabat
Military Hospital Mohammed V
El-Hamzaoui, Sakina Amara
Morocco, Agdal Rabat
Military Hospital Mohammed V
Frikh, Mohammed
Morocco, Agdal Rabat
Military Hospital Mohammed V
Zrara, Abdelhamid
Morocco, Agdal Rabat
Military Hospital Mohammed V
Chagar, Belkacem
Morocco, Agdal Rabat
Military Hospital Mohammed V
Ouaaline, M.
Morocco, Agdal Rabat
Military Hospital Mohammed V
Statistics
Citations: 6
Authors: 6
Affiliations: 1
Identifiers
Doi:
10.1016/j.medmal.2007.04.002
ISSN:
0399077X
Research Areas
Health System And Policy
Study Design
Cohort Study