Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

medicine

Ebola Virus Disease Diagnostics, Sierra Leone: Analysis of Real-time Reverse Transcription-Polymerase Chain Reaction Values for Clinical Blood and Oral Swab Specimens

Journal of Infectious Diseases, Volume 214, Year 2016

During the Ebola virus outbreak of 2013-2016, the Viral Special Pathogens Branch field laboratory in Sierra Leone tested approximately 26 000 specimens between August 2014 and October 2015. Analysis of the B2M endogenous control Ct values showed its utility in monitoring specimen quality, comparing results with different specimen types, and interpretation of results. For live patients, blood is the most sensitive specimen type and oral swabs have little diagnostic utility. However, swabs are highly sensitive for diagnostic testing of corpses.

Erickson, B. R.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Sealy, Tara K.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Flietstra, Timothy D.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Morgan, Laura
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Kargbo, Brima Ibrahim Baimba
1. Sierra Leone, Freetown Ministry of Health and Sanitation
Matt-Lebby, Victor E.
1. Sierra Leone, Freetown Ministry of Health and Sanitation
Gibbons, Aridth
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Chakrabarti, Ayan K.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Graziano, James C.
1. United States Bacterial Special Pathogens Branch
Presser, Lance D.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Flint, Mike
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Bird, Brian H.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Brown, Shelley M.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Klena, John David
1. United States, Atlanta Centers for Disease Control and Prevention
Blau, Dianna M.
1. United States Infectious Diseases Pathology Branch
Brault, A.
1. Australia Arboviral Diseases Branch
Belser, Jessica A.
1. United States, Atlanta Influenza Division
Salzer, Johanna S.
1. United States Pox and Rabies Branch
Schuh, Amy J.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Lo, Michael
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Zivcec, Marko
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Priestley, Rachael A.
1. United States Rickettsial Zoonoses Branch
Pyle, Meredith
1. United States, Atlanta Coordinating Center for Health Promotion
Goodman, Christin H.
1. Australia Arboviral Diseases Branch
Bearden, Scott
1. United States, Atlanta Centers for Disease Control and Prevention
Amman, Brian R.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Basile, Alison Jane
1. Australia Arboviral Diseases Branch
Bergeron, Éric
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Bowen, Michael D.
1. United States Gastroenteritis and Respiratory Virus Laboratory Branch
Dodd, Kimberly A.
1. United States, Davis School of Veterinary Medicine
Freeman, Molly M.
1. United States Enteric Diseases Laboratory Branch
McMullan, Laura K.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Paddock, Christopher D.
1. United States Rickettsial Zoonoses Branch
Russell, Brandy J.
1. Australia Arboviral Diseases Branch
Sanchez, Angela J.
1. United States, Boston Office of Technology and Innovation
Towner, Jonathan S.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Wang, David
1. United States, Atlanta Influenza Division
Zemtsova, Galina E.
1. United States Rickettsial Zoonoses Branch
Stoddard, Robyn Anne
1. United States Bacterial Special Pathogens Branch
Turnsek, Maryann
1. United States Enteric Diseases Laboratory Branch
Guerrero, Lisa I.W.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Emery, Shannon L.
1. United States, Little Rock Virology
Stovall, Janae
1. Australia Arboviral Diseases Branch
Kainulainen, Markus H.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Perniciaro, Jamie L.
1. United States Rickettsial Zoonoses Branch
Mijatovic-Rustempasic, Slavica
1. United States Gastroenteritis and Respiratory Virus Laboratory Branch
Shakirova, Gulchekhra
1. United States Inorganic and Radiation Analytical Toxicology Branch
Winter, J.
1. United States, Little Rock Virology
Sexton, Christopher
1. United States, Atlanta Centers for Disease Control and Prevention
Liu, Feng
1. United States, Atlanta Influenza Division
Slater, Kimetha
1. United States Rickettsial Zoonoses Branch
Anderson, Raydel D.
1. Australia Herpes Virus Laboratory Branch
Andersen, Lauren E.
1. United States, Atlanta Laboratory Preparedness and Response Branch
Chiang, Cheng-Feng
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Tzeng, Wen Pin
1. United States, Atlanta Influenza Division
Crowe, Samuel J.
1. United States Enteric Diseases Epidemiology Branch
Maenner, Matthew J.
1. United States, Atlanta Centers for Disease Control and Prevention
Spiropoulou, Christina F.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Nichol, Stuart T.
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases
Ströher, Ute
1. United States, Atlanta National Center for Emerging and Zoonotic Infectious Diseases

AFRICAN RESEARCH NEXUS

Ebola Virus Disease Diagnostics, Sierra Leone: Analysis of Real-time Reverse Transcription-Polymerase Chain Reaction Values for Clinical Blood and Oral Swab Specimens

Disclaimer

African Research Nexus

Useful Links

AFRICAN RESEARCH NEXUS

Ebola Virus Disease Diagnostics, Sierra Leone: Analysis of Real-time Reverse Transcription-Polymerase Chain Reaction Values for Clinical Blood and Oral Swab Specimens

Description

Authors & Co-Authors

Disclaimer

African Research Nexus

Useful Links