Importance of clonal complex 258 and IncFK2-like plasmids among a global collection of Klebsiella pneumoniae with blaKPC

This study was designed to determine the global distribution of clonal complex (CC) 258 and IncFIIK2-like plasmids with blaKPC among 522 global Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae isolates. CC258 (i.e., ST258 [clades I and II], ST11, ST340, and ST512) and ST147 were statistically associated with IncFIIK2-like KPC-containing plasmids and may possess an epidemiological advantage over isolates that harbored non-IncF KPC-harboring plasmids.