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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Family cluster of middle east respiratory syndrome coronavirus infections
New England Journal of Medicine, Volume 368, No. 26, Year 2013
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Description
A human coronavirus, called the Middle East respiratory syndrome coronavirus (MERS-CoV), was first identified in September 2012 in samples obtained from a Saudi Arabian businessman who died from acute respiratory failure. Since then, 49 cases of infections caused by MERS-CoV (previously called a novel coronavirus) with 26 deaths have been reported to date. In this report, we describe a family case cluster of MERS-CoV infection, including the clinical presentation, treatment outcomes, and household relationships of three young men who became ill with MERS-CoV infection after the hospitalization of an elderly male relative, who died of the disease. Twenty-four other family members living in the same household and 124 attending staff members at the hospitals did not become ill. MERS-CoV infection may cause a spectrum of clinical illness. Although an animal reservoir is suspected, none has been discovered. Meanwhile, global concern rests on the ability of MERS-CoV to cause major illness in close contacts of patients. Copyright © 2013 Massachusetts Medical Society.
Authors & Co-Authors
Al Memish, Ziad Ahmed
Saudi Arabia, Riyadh
Global Centre for Mass Gatherings Medicine
Saudi Arabia, Riyadh
Ministry of Health Saudi Arabia
Saudi Arabia, Riyadh
Alfaisal University
Zumla, A. I.
Saudi Arabia, Riyadh
Global Centre for Mass Gatherings Medicine
United Kingdom, London
University College London
United Kingdom, London
University College London Hospitals Nhs Foundation Trust
Al Hakeem, Rafat Faisal
Saudi Arabia, Riyadh
Global Centre for Mass Gatherings Medicine
Saudi Arabia, Riyadh
Ministry of Health Saudi Arabia
Al-Rabeeah, Abdullah A.
Saudi Arabia, Riyadh
Global Centre for Mass Gatherings Medicine
Saudi Arabia, Riyadh
Ministry of Health Saudi Arabia
Stephens, Gwen M.
Saudi Arabia, Riyadh
Global Centre for Mass Gatherings Medicine
Saudi Arabia, Riyadh
Ministry of Health Saudi Arabia
Statistics
Citations: 529
Authors: 5
Affiliations: 5
Identifiers
Doi:
10.1056/NEJMoa1303729
ISSN:
00284793
e-ISSN:
15334406
Research Areas
Covid
Participants Gender
Male