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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The influence of hip circumference on the relationship between abdominal obesity and mortality
International Journal of Epidemiology, Volume 41, No. 2, Article dyr198, Year 2012
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Description
Background: Higher waist circumference and lower hip circumference are both associated with increased cardiovascular disease (CVD) risk, despite being directly correlated. The real effects of visceral obesity may therefore be underestimated when hip circumference is not fully taken into account. We hypothesized that adding waist and hip circumference to traditional risk factors would significantly improve CVD risk prediction. Methods: In a population-based survey among South Asian and African Mauritians (n = 7978), 1241 deaths occurred during 15 years of follow-up. In a model that included variables used in previous CVD risk calculations (a Framingham-type model), the association between waist circumference and mortality was examined before and after adjustment for hip circumference. The percentage with an increase in estimated 10-year cumulative mortality of >25% and a decrease of >20% after waist and hip circumference were added to the model was calculated. Results: Waist circumference was strongly related to mortality only after adjustment for hip circumference and vice versa. Adding waist and hip circumference to a Framingham-type model increased estimated 10-year cumulative CVD mortality by >25% for 23.7% of those who died and 15.7% of those censored. Cumulative mortality decreased by >20% for 4.5% of those who died and 14.8% of those censored. Conclusions: The effect of central obesity on mortality risk is seriously underestimated without adjustment for hip circumference. Adding waist and hip circumference to a Framingham-type model for CVD mortality substantially increased predictive power. Both may be important inclusions in CVD risk prediction models. Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2012; all rights reserved.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC3324456/bin/supp_41_2_484__index.html
https://efashare.b-cdn.net/share/pmc/articles/PMC3324456/bin/supp_dyr198_ije-2011-04-0378-File001.doc
Authors & Co-Authors
Cameron, Adrian J.
Australia, Melbourne
Baker Heart and Diabetes Institute
Australia, Melbourne
The Institute for Physical Activity and Nutrition
Magliano, Dianna J.
Australia, Melbourne
Baker Heart and Diabetes Institute
Australia, Clayton
Monash University
Shaw, Jonathan E.
Australia, Melbourne
Baker Heart and Diabetes Institute
Zimmet, Paul Z.
Australia, Melbourne
Baker Heart and Diabetes Institute
Carstensen, Bendix
Denmark, Herlev
Steno Diabetes Center Copenhagen
Alberti, Kurt George M.M.A.
United Kingdom, London
St Mary's Hospital
Tuomilehto, Jaakko O.I.
Finland, Helsinki
Helsingin Yliopisto
Finland, Seinajoki
South Ostrobothnia Central Hospital
Spain, Madrid
Hospital Universitario la Paz
Barr, Elizabeth L.M.
Australia, Melbourne
Baker Heart and Diabetes Institute
Pauvaday, Vassen K.
Mauritius, Port Louis
Ministry of Health and Quality of Life
Kowlessur, Sudhir
Mauritius, Port Louis
Ministry of Health and Quality of Life
Söderberg, Stefan
Australia, Melbourne
Baker Heart and Diabetes Institute
Sweden, Umea
Umeå Universitet
Statistics
Citations: 96
Authors: 11
Affiliations: 10
Identifiers
Doi:
10.1093/ije/dyr198
ISSN:
03005771
e-ISSN:
14643685
Research Areas
Noncommunicable Diseases
Study Design
Cross Sectional Study
Cohort Study
Study Approach
Quantitative