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AFRICAN RESEARCH NEXUS

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neuroscience

Effects of electroconvulsive therapy on regional cerebral blood flow measured by 99mtechnetium HMPAO SPECT

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Volume 27, No. 1, Year 2003

Decreased cerebral blood flow is documented in depression. In this study, 15 patients were studied with 99mTc-HMPAO SPECT before and after a course of electroconvulsive therapy (ECT). Improvement in frontal and temporal hypoperfusion was seen only in those patients who responded to ECT. Cerebral hypoperfusion may be a state-dependent marker in depressive illness. © 2002 Elsevier Science Inc. All rights reserved.
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Citations: 41
Authors: 4
Affiliations: 1
Research Areas
Mental Health