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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Infectious complications in kidney transplant: A lebanese perspective
Experimental and Clinical Transplantation, Volume 8, No. 2, Year 2010
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Description
Objectives: Infections remain a frequent, potentially life-threatening complication of kidney transplant. Subjects and Methods: Between 1998 and 2006, we evaluated the incidence of infections in 114 kidney transplant patients, with a 1-year follow-up. All patients received a posttransplant anti-infectious prophylaxis regimen. Induction therapy was given to 94 patients (82.4%), and maintenance immunosuppression consisted of calcineurin inhibitor (cyclosporin microemulsion or tacrolimus), together with mycophenolate mofetil and prednisone. Results: In total, 56 patients (49.1%) developed a total of 95 infections up to 1-year after kidney transplant, including 46 in-hospital infections in 38 patients. Bacterial infections were the most frequent (97.8%), and were mainly urinary, followed by drain, central line catheter, and pulmonary infections. The most-frequent isolated bacteria were E. coli, followed by Klebsiella, Acinetobacter, and Pseudomonas. No viral infections were detected. Up to 1 year after discharge from the hospital, 49 infections occurred in 26 patients, of which 79.5% were bacterial; mainly urinary tract infections due to E. coli, in addition to 7 cases of cytomegalovirus, 1 herpes, and 2 cases of fungal infections. Conclusions: This is the first Lebanese study that deals with posttransplant infections in kidney transplant patients and underscores the importance of close patient monitoring and follow-up. Comparison with international data shows similar patterns. © Baskent University 2003.
Authors & Co-Authors
Abou-Jaoudé, Maroun M.
Lebanon, Baabda
Sacre-coeur Hospital, Baabda
Lebanon, Beirut
St. Georges University Hospital
Lebanon, Al Koura
University of Balamand
Nawfal, Naji
Lebanon, Baabda
Sacre-coeur Hospital, Baabda
Shaheen, Joseph
Lebanon, Baabda
Sacre-coeur Hospital, Baabda
Daoud, Ziad D.
Lebanon, Al Koura
University of Balamand
Almawi, Wassim Y.
Bahrain, Manama
Arabian Gulf University
Statistics
Citations: 5
Authors: 5
Affiliations: 4
Identifiers
ISSN:
13040855
Research Areas
Health System And Policy
Study Design
Cohort Study