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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Basal cell carcinoma in five albino Africans from the south-eastern equatorial rain forest of Nigeria
International Journal of Dermatology, Volume 46, No. 7, Year 2007
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Description
Background: Basal cell carcinoma (BCC) is the most common cutaneous malignancy in the white population and occurs infrequently in dark-pigmented individuals. Albinism is an established risk factor for skin cancer in black Africans. Methods: We evaluated the clinical histories and treatment outcomes of patients with a histologic diagnosis of BCC, who were seen at the University of Calabar Teaching Hospital, Calabar, Nigeria between January 2000 and December 2004. Results: Five albino Nigerians (two men, three women) with BCC represented 8% of the patients with cutaneous malignancies observed during the 5-year period. The five patients ranged in age from 21 to 60 years (mean, 38 years); six BCCs 67%) were located in the head and neck area, and three tumors (33%) involved the upper limbs. Lesions were removed by excision with primary closure, except for large fleshy tumors that were treated by excision and electrocautery. During evaluation from 9 months to 3 years after treatment, all sites appeared healed, and there was no evidence of recurrence or new tumors. Conclusions: Albinism and environmental exposure to ultraviolet light were identified as risk factors for the development of BCC. Implementation of public education strategies concerning prevention would improve the prognosis and healthcare costs associated with these tumors. © 2007 The International Society of Dermatology.
Authors & Co-Authors
Asuquo, M. E.
Nigeria, Calabar
University of Calabar
Agweye, Pius
Nigeria, Calabar
University of Calabar
Ugare, Gabriel
Nigeria, Calabar
University of Calabar
Ebughe, Godwin
Nigeria, Calabar
University of Calabar
Statistics
Citations: 25
Authors: 4
Affiliations: 1
Identifiers
Doi:
10.1111/j.1365-4632.2007.03272.x
ISSN:
00119059
e-ISSN:
13654632
Research Areas
Cancer
Health System And Policy
Study Design
Cross Sectional Study
Study Locations
Nigeria
Participants Gender
Male
Female