Publication Details

AFRICAN RESEARCH NEXUS

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medicine

Lab-on-chip-based platform for fast molecular diagnosis of multidrug-resistant tuberculosis

Journal of Clinical Microbiology, Volume 53, No. 12, Year 2015

We evaluated the performance of the molecular lab-on-chip-based VerePLEX Biosystem for detection of multidrug-resistant tuberculosis (MDR-TB), obtaining a diagnostic accuracy of more than 97.8% compared to sequencing and MTBDRplus assay for Mycobacterium tuberculosis complex and rifampin and isoniazid resistance detection on clinical isolates and smear-positive specimens. The speed, user-friendly interface, and versatility make it suitable for routine laboratory use.

Statistics
Citations: 43
Authors: 24
Affiliations: 13
Identifiers
Doi: 10.1128/JCM.01824-15
ISSN: 00951137
e-ISSN: 1098660X
Research Areas
Infectious Diseases

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