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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Radiofrequency facial rejuvenation: Evidence-based effect
Journal of the American Academy of Dermatology, Volume 64, No. 3, Year 2011
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Description
Background: Multiple therapies involving ablative and nonablative techniques have been developed for rejuvenation of photodamaged skin. Monopolar radiofrequency (RF) is emerging as a gentler, nonablative skin-tightening device that delivers uniform heat to the dermis at a controlled depth. Objective: We evaluated the clinical effects and objectively quantified the histologic changes of the nonablative RF device in the treatment of photoaging. Methods: Six individuals of Fitzpatrick skin type III to IV and Glogau class I to II wrinkles were subjected to 3 months of treatment (6 sessions at 2-week intervals). Standard photographs and skin biopsy specimens were obtained at baseline, and at 3 and 6 months after the start of treatment. We performed quantitative evaluation of total elastin, collagen types I and III, and newly synthesized collagen using computerized histometric and immunohistochemical techniques. Blinded photographs were independently scored for wrinkle improvement. Results: RF produced noticeable clinical results, with high satisfaction and corresponding facial skin improvement. Compared with the baseline, there was a statistically significant increase in the mean of collagen types I and III, and newly synthesized collagen, while the mean of total elastin was significantly decreased, at the end of treatment and 3 months posttreatment. Limitations: A limitation of this study is the small number of patients, yet the results show a significant improvement. Conclusions: Although the results may not be as impressive as those obtained by ablative treatments, RF is a promising treatment option for photoaging with fewer side effects and downtime. © 2009 by the American Academy of Dermatology, Inc.
Authors & Co-Authors
El-Domyati, Moetaz M.M.
Egypt, Minya
Minia University
El-Ammawi, Tarek S.
Egypt, Minya
Minia University
Medhat, Walid
Egypt, Minya
Minia University
United States, Philadelphia
Thomas Jefferson University
Moawad, Osama
Egypt, Cairo
Moawad Skin Institute for Laser
Brennan-Crispi, Donna M.
United States, Philadelphia
Thomas Jefferson University
Mahoney, Mỹ G.
United States, Philadelphia
Thomas Jefferson University
Uitto, Jouni J.
United States, Philadelphia
Thomas Jefferson University
Statistics
Citations: 142
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/j.jaad.2010.06.045
ISSN:
01909622
Research Areas
Health System And Policy
Study Approach
Quantitative