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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Evaluation of a contactless neonatal physiological monitor in Nairobi, Kenya
Archives of Disease in Childhood, Volume 107, No. 6, Year 2022
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Description
Background Globally, 2.5 million neonates died in 2018, accounting for 46% of under-5 deaths. Multiparameter continuous physiological monitoring (MCPM) of neonates allows for early detection and treatment of life-threatening health problems. However, neonatal monitoring technology is largely unavailable in low-resource settings. Methods In four evaluation rounds, we prospectively compared the accuracy of the EarlySense under-mattress device to the Masimo Rad-97 pulse CO-oximeter with capnography reference device for heart rate (HR) and respiratory rate (RR) measurements in neonates in Kenya. EarlySense algorithm optimisations were made between evaluation rounds. In each evaluation round, we compared 200 randomly selected epochs of data using Bland-Altman plots and generated Clarke error grids with zones of 20% to aid in clinical interpretation. Results Between 9 July 2019 and 8 January 2020, we collected 280 hours of MCPM data from 76 enrolled neonates. At the final evaluation round, the EarlySense MCPM device demonstrated a bias of −0.8 beats/ minute for HR and 1.6 breaths/minute for RR, and normalised spread between the 95% upper and lower limits of agreement of 6.2% for HR and 27.3% for RR. Agreement between the two MCPM devices met the a priori–defined threshold of 30%. The Clarke error grids showed that all observations for HR and 197/200 for RR were within a 20% difference. Conclusion Our research indicates that there is acceptable agreement between the EarlySense and Masimo MCPM devices in the context of large within-subject variability; however, further studies establishing cost-effectiveness and clinical effectiveness are needed before large-scale implementation of the EarlySense MCPM device in neonates. © Author(s) (or their employer(s)) 2022.
Authors & Co-Authors
Macharia, W. M.
Pakistan, Karachi
The Aga Khan University
Ochieng, Roseline
Pakistan, Karachi
The Aga Khan University
Chomba, Dorothy
Pakistan, Karachi
The Aga Khan University
Karasik, Roman
Unknown Affiliation
Dunsmuir, Dustin T.
Canada, Vancouver
The University of British Columbia
Coleman, Jesse
Canada, Vancouver
Centre for International Child Health
Zhou, Guohai
United States, Boston
Brigham and Women's Hospital
Ginsburg, Amy Sarah
United States, Seattle
University of Washington
Ansermino, John Mark
Canada, Vancouver
The University of British Columbia
Statistics
Citations: 1
Authors: 9
Affiliations: 5
Identifiers
Doi:
10.1136/archdischild-2021-322344
ISSN:
00039888
Research Areas
Maternal And Child Health
Study Locations
Kenya