Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Assessing the reporting of adherence and sexual activity in a simulated microbicide trial in South Africa: An interview mode experiment using a placebo gel
AIDS and Behavior, Volume 15, No. 2, Year 2011
Notification
URL copied to clipboard!
Description
Misreporting of adherence undermines detection of an association between product use and HIV infection in microbicide trials. This study investigates whether, in a placebo trial, audio computer-assisted self-interviewing (ACASI) produces more accurate reporting of adherence and sexual behavior than a face-to-face interview (FTFI). At three South African clinics, 849 women were enrolled and instructed to use applicators filled with placebo gel; participants were randomly assigned to FTFI or ACASI. Behavioral reports were validated through two biomarkers that detect product usage and unprotected sex. For most behaviors, ACASI generated significantly higher reporting, although differences by interview mode appeared to diminish over time. ACASI participants were more likely to report having had sex without gel, but reported and tested applicators did not indicate greater honesty about gel insertion with ACASI. While comparisons of reported unprotected sex with the validated biomarker revealed more agreement with ACASI than with FTFI, differences were small. © 2010 Springer Science+Business Media, LLC.
Authors & Co-Authors
Mensch, Barbara Sena
United States, New York
The Population Council, Inc.
Hewett, Paul C.
Zambia, Lusaka
Population Council
Abbott, Sharon A.
United States, New York
The Population Council, Inc.
Rankin, Johanna C.
United States, New York
The Population Council, Inc.
Littlefield, Sarah
United States, New York
The Population Council, Inc.
Ahmed, Khatija
South Africa, Pretoria
Sefako Makgatho Health Sciences University Smu
Cassim, Nazira
South Africa, Pretoria
Sefako Makgatho Health Sciences University Smu
Patel, Smruti
South Africa, Cape Town
University of Cape Town
Ramjee, Gita A.
South Africa, Tygerberg
South African Medical Research Council
Palanee-Phillips, Thesla
South Africa, Johannesburg
Chris Hani Baragwanath Hospital
Mierzwa, Stan
United States, New York
The Population Council, Inc.
Skoler-Karpoff, Stephanie
United States, New York
Memorial Sloan-kettering Cancer Center
Statistics
Citations: 50
Authors: 12
Affiliations: 7
Identifiers
Doi:
10.1007/s10461-010-9791-z
ISSN:
10907165
Research Areas
Infectious Diseases
Sexual And Reproductive Health
Study Approach
Quantitative
Study Locations
South Africa
Participants Gender
Female