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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Towards elimination of mother-to-child transmission of HIV: The impact of a rapid results initiative in nyanza province, Kenya
AIDS Research and Treatment, Volume 2012, Article 602120, Year 2012
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Description
Many HIV-positive pregnant women and infants are still not receiving optimal services, preventing the goal of eliminating mother-to-child transmission (MTCT) and improving maternal child health overall. A Rapid Results Initiative (RRI) approach was utilized to address key challenges in delivery of prevention of MTCT (PMTCT) services including highly active antiretroviral therapy (HAART) uptake for women and infants. The RRI was conducted between April and June 2011 at 119 health facilities in five districts in Nyanza Province, Kenya. Aggregated site-level data were compared at baseline before the RRI (Oct 2010-Jan 2011), during the RRI, and post-RRI (Jul-Sep 2011) using pre-post cohort analysis. HAART uptake amongst all HIV-positive pregnant women increased by 40% (RR 1.4, 95% CI 1.2-1.7) and continued to improve post-RRI (RR 1.6, 95% CI 1.4-1.8). HAART uptake in HIV-positive infants remained stable (RR 1.1, 95% CI 0.9-1.4) during the RRI and improved by 30% (RR 1.3, 95% CI 1.0-1.6) post-RRI. Significant improvement in PMTCT services can be achieved through introduction of an RRI, which appears to lead to sustained benefits for pregnant HIV-infected women and their infants. © 2012 Lisa L. Dillabaugh et al.
Authors & Co-Authors
Dillabaugh, Lisa L.
United States, San Francisco
University of California, San Francisco
Kenya, Nairobi
Kenya Medical Research Institute
Lewis-Kulzer, Jayne
Kenya, Nairobi
Kenya Medical Research Institute
Owuor, Kevin Omondi
Kenya, Nairobi
Kenya Medical Research Institute
Ndege, Valeria
Kenya, Nairobi
Kenya Medical Research Institute
Oyanga, Arbogast O.
Kenya, Nairobi
Kenya Medical Research Institute
Ngugi, Evelyn W.
United States, Atlanta
Centers for Disease Control and Prevention
Shade, Starley B.
Kenya, Nairobi
Kenya Medical Research Institute
Bukusi, Elizabeth Anne
Kenya, Nairobi
Kenya Medical Research Institute
United States, San Francisco
University of California, San Francisco
Cohen, Craig R.
Kenya, Nairobi
Kenya Medical Research Institute
United States, San Francisco
University of California, San Francisco
Statistics
Citations: 31
Authors: 9
Affiliations: 3
Identifiers
Doi:
10.1155/2012/602120
e-ISSN:
20901259
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cohort Study
Study Locations
Kenya
Participants Gender
Female