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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
ACQUIRED IMMUNODEFICIENCY SYNDROME IS AN OPPORTUNISTIC INFECTION AND KAPOSI'S SARCOMA RESULTS FROM SECONDARY IMMUNE STIMULATION
The Lancet, Volume 322, No. 8341, Year 1983
Notification
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Description
Two hypotheses are presented to explain the recent outbreak of acquired immunodeficiency syndrome (AIDS) and Kaposi's sarcoma in certain risk groups, particularly homosexuals, and the absence of these diseases from other segments of the population. According to the first, AIDS is itself an opportunistic infection. It causes disease only in individuals who are already immuno-compromised by hepatitis B, cytomegalovirus, parasites, or other immunosuppressive factors. This hypothesis predicts that evidence of previous contact with the AIDS agent would be found in healthy individuals who have had the immune capability to suppress its pathogenicity. It also suggests that individuals with evidence of immunodeficiency are at risk of this syndrome and should adopt a lifestyle favouring recovery of their immune system. According to the second hypothesis, the high incidence of Kaposi's sarcoma observed in immunocompromised AIDS patients is not due to decreased. © 1983.
Authors & Co-Authors
Levy, Jay As
United States, San Francisco
Ucsf School of Medicine
Ziegler, John L.
United States, San Francisco
Ucsf School of Medicine
Statistics
Citations: 115
Authors: 2
Affiliations: 1
Identifiers
Doi:
10.1016/S0140-6736(83)90062-4
ISSN:
01406736
Research Areas
Cancer
Infectious Diseases
Study Design
Cross Sectional Study
Cohort Study