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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Cardiovascular risk factors in adult Malawians on long-term antiretroviral therapy
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 105, No. 11, Year 2011
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Description
Around 225 000 patients currently receive antiretroviral therapy (ART) in the Malawi scale-up programme that uses the public health approach to ART. There are concerns that cardiovascular disease risk factors are common in ART patients, but few data exist from sub-Saharan Africa, and none from Malawi. We did a cross-sectional study of cardiovascular risk factors in urban, adult, Malawian ART patients, with the WHO STEP-wise surveillance tool.We enrolled 174 long-term (>1 year) ART patients during routine clinic visits, mean age 40.8 years (range 18-69), 61.5% female, 97.1% on first-line regimens, median duration ART 35.5 months. Insufficient fruit and vegetable diet (67.6%), raised blood pressure (45.9%), increased waist-hip ratio (45.4%), raised total cholesterol levels (31.0%) and low physical activity level (27.0%) were common, while current smoking (0.6%), current alcohol consumption (2.3%) and elevated glucose levels (1.2%) were rare. In multivariable analyses, higher age was associated with low physical activity, raised blood pressure, being overweight, and increased waist-hip ratio. Longer duration of ART was not associated with any risk factor and was protective for being overweight.Cardiovascular risk factors were common among long-term ART patients in Malawi. This requires more attention and further study in programmes using the public health approach to ART. © 2011 Royal Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Muronya, William
Malawi, Zomba
University of Malawi
Sanga, Erica Samson
Malawi, Zomba
University of Malawi
Talama, George C.
Malawi, Zomba
University of Malawi
Kumwenda, Johnstone J.
Malawi, Zomba
University of Malawi
van Oosterhout, Joep J.G.
Malawi, Zomba
University of Malawi
Statistics
Citations: 50
Authors: 5
Affiliations: 1
Identifiers
Doi:
10.1016/j.trstmh.2011.07.016
ISSN:
00359203
e-ISSN:
18783503
Research Areas
Health System And Policy
Noncommunicable Diseases
Substance Abuse
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Malawi
Participants Gender
Female